(-)-γ-Cuparenol
(-)-γ-Cuparenol is a sesquiterpene compound with an IC50 of 23.6 μg/mL against porcine Na+/K+-ATPase. (-)-γ-Cuparenol reduces phytohemagglutinin (PHA)-induced activation of NF-AT and NF-κB in Jurkat cells. (-)-γ-Cuparenol inhibits the growth of Gram-positive bacteria and some Gram-negative bacteria. (-)-γ-Cuparenol exhibits weak inhibitory activity against Candida albicans. (-)-γ-Cuparenol is applicable for research related to immunoregulation, cardiovascular diseases and bacterial infections.
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- CAS No.: 1357469-94-3
- 화학식: C15H22O
- 분자량:218.33
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
(-)-γ-Cuparenol (10 μg/mL; 4 h) significantly reduces PHA-induced NF-AT and NF-κB activation in Jurkat T lymphocytes[1].
(-)-γ-Cuparenol (0.05-100 μg/mL; 24 h ) inhibits the growth of Staphylococcus aureus, Bacillus subtilis, Micrococcus luteus, Proteus vulgaris, and Salmonella typhimurium with an MIC of 50 μg/mL, but does not inhibit Escherichia coli growth at concentrations up to 100 μg/mL[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1357469-94-3
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분자량 218.33
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화학식 C15H22O
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SMILES
C[C@@]1(C2=CC=C(C=C2)CO)C(C)(CCC1)C
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(-)-γ-Cuparenol Related Classifications
HY-N17413 Related Classifications
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