1357469-94-3
Chemical Structure
(-)-γ-Cuparenol
- CAS No.: 1357469-94-3
- Formula:C15H22O
- Molecular Weight:218.33
InChIKey: ZAOGHPYFYBQFLS-OAHLLOKOSA-N
SMILES: C[C@@]1(C2=CC=C(C=C2)CO)C(C)(CCC1)C
Biological Activity: (-)-γ-Cuparenol is a sesquiterpene compound with an IC50 of 23.6 μg/mL against porcine Na+/K+-ATPase. (-)-γ-Cuparenol reduces phytohemagglutinin (PHA)-induced activation of NF-AT and NF-κB in Jurkat cells. (-)-γ-Cuparenol inhibits the growth of Gram-positive bacteria and some Gram-negative bacteria. (-)-γ-Cuparenol exhibits weak inhibitory activity against Candida albicans. (-)-γ-Cuparenol is applicable for research related to immunoregulation, cardiovascular diseases and bacterial infections[1][2].
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(-)-γ-Cuparenol | (-)-γ-Cuparenol is a sesquiterpene compound with an IC50 of 23.6 μg/mL against porcine Na+/K+-ATPase. (-)-γ-Cuparenol reduces phytohemagglutinin (PHA)-induced activation of NF-AT and NF-κB in Jurkat cells. (-)-γ-Cuparenol inhibits the growth of Gram-positive bacteria and some Gram-negative bacteria. (-)-γ-Cuparenol exhibits weak inhibitory activity against Candida albicans. (-)-γ-Cuparenol is applicable for research related to immunoregulation, cardiovascular diseases and bacterial infections. | |||||||||||||||||||||
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- [1]. Khongorzul Mendbayar, et al. New and Bioactive Sesquiterpenes from Schisandra sphenanthera. Wiley, 08 December 2011.
- [2]. Oh I, et al. In vitro Na+/K+-ATPase inhibitory activity and antimicrobial activity of sesquiterpenes isolated from Thujopsis dolabrata. Arch Pharm Res. 2011;34(12):2141-2147. [Content Brief]
Keywords
