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Cat. No.: HY-P10965

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Zovaglutide

(Synonyms: ZT002)

Zovaglutide (ZT002) is a long-acting, selective GLP-1 receptor agonist. Zovaglutide enhances albumin binding capacity via dual fatty acid chain modification. Zovaglutide exerts metabolic effects through central and peripheral GLP-1 pathways, thereby promoting satiety, reducing caloric intake and enhancing glucose-dependent insulin secretion, with no activity against GIP or glucagon receptors. Zovaglutide can be used in research on type 2 diabetes or obesity.

For research use only. We do not sell to patients.

CAS No.: 3013543-64-8
Formula: C₃₇₄H₅₈₄N₉₆O₁₂₃
Molecular Weight:8393.21

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Zovaglutide Chemical Structure

CAS No.: 3013543-64-8

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Sample (0.1mg)

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

GLP-1

In Vitro

Zovaglutide enhances albumin-binding capacity via dual fatty acid chain modification, thereby prolonging systemic exposure time^[1].
Zovaglutide exerts metabolic effects via central and peripheral GLP-1 pathways, thereby promoting satiety, reducing caloric intake, and enhancing glucose-dependent insulin secretion^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3013543-64-8
Molecular Weight 8393.21
Formula C₃₇₄H₅₈₄N₉₆O₁₂₃
Synonyms

ZT002
Sequence

His-{Aib}Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Glu-Gln-Ala-Ala-{Lys(AEEA-AEEA-gGlu-C18 diacid)}-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Gly-Gly-Gly-Ala-Gln-Pro-Gly-Ala-Gln-Pro-Gly-Ala-Gln-Pro-Gly-Ala-Gln-Pro-Gly-Ala-Gln-Pro-Gly-Ala-Gln-Pro-Gly-Ala-Gln-Pro-Gly-Ala-Gln-Pro-Gly-Ala-Gln-Pro-Gly-Gln-{Lys(AEEA-AEEA-gGlu-C18 diacid)}-Pro
Sequence Shortening

H-{Aib}-EGTFTSDVSSYLEEQAA-{Lys(AEEA-AEEA-gGlu-C18 diacid)}-EFIAWLVRGGGGAQPGAQPGAQPGAQPGAQPGAQPGAQPGAQPGAQPGQ-{Lys(AEEA-AEEA-gGlu-C18 diacid)}-P
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Saldívar-Cerón H I. Once-Monthly and Extended-Interval Incretin-, Amylin-, and THRβ-Targeting Therapies for Type 2 Diabetes and Obesity: Clinical Evidence and Development Pipelines[J]. Scientia Pharmaceutica, 2026, 94(1): 21.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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