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Results for "

polyphylla

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

8

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0047
    Polyphyllin I
    5 Publications Verification

    		 JNK mTOR Akt PDK-1 Autophagy Apoptosis Cancer
    Polyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and is an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis .
    Polyphyllin I
  • HY-N2382
    Polyphyllin H
    1 Publications Verification

    		 Cytochrome P450 P-glycoprotein Metabolic Disease Cancer
    Polyphyllin H is a steroidal saponin. Polyphyllin H is isolated from Paris polyphylla. Polyphyllin H potently inhibits the activities of CYP1A2 (IC50 = 6.44 μM, competitive), CYP2D6 (IC50 = 13.88 μM, competitive) and CYP3A4 (IC50 = 4.52 μM, non-competitive, time-dependent). Polyphyllin H downregulates the expression of ABCB1 and ABCC3. Polyphyllin H binds to membrane cholesterol and disrupts lipid raft structures. Polyphyllin H restores the sensitivity of paclitaxel-resistant breast cancer cells to paclitaxel .
    Polyphyllin H
  • HY-N0047R
    Polyphyllin I (Standard)

    		Reference Standards JNK mTOR Akt PDK-1 Autophagy Apoptosis Cancer
    Polyphyllin I (Standard) is the analytical standard of Polyphyllin I. This product is intended for research and analytical applications. Polyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and is an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis .
    Polyphyllin I (Standard)
  • HY-N12002
    Diosgenin-3-O-rhamnosyl(1→2)[glucosyl(1→6)]glucoside

    		Others Others
    Diosgenin-3-O-rhamnosyl(1→2)[glucosyl(1→6)]glucoside (compound 9) is a steroidal saponin, which can be obtained from Paris polyphylla var., Yunnan pine (yunnanensis) Isolated .
    Diosgenin-3-O-rhamnosyl(1→2)[glucosyl(1→6)]glucoside
  • HY-N3389A
    (S)-Licoisoflavone A

    Dihydrolicoisoflavone

    		 Others Others
    (S)-Licoisoflavone A (Dihydrolicoisoflavone) is an isoflavanone that can be isolated from swartzia polyphylla .
    (S)-Licoisoflavone A
  • HY-N12065
    Parisyunnanoside H

    		Others Others
    Parisyunnanoside H is a steroidal saponin isolated from Paris polyphylla Smith var. yunnanensis .
    Parisyunnanoside H
  • HY-N2389R
    Formosanin C (Standard)

    		Reference Standards Apoptosis Cancer
    Formosanin C (Standard) is the analytical standard of Formosanin C. This product is intended for research and analytical applications. Formosanin C is a diosgenin saponin isolated from Paris polyphylla and an immunomodulator with antitumor activity. Formosanin C induces apoptosis .
    Formosanin C (Standard)
  • HY-169812
    Dihydrobiochanin A

    		Fungal Infection
    Dihydrobiochanin A has antifungal activity. Dihydrobiochanin A is a flavonoid that can isolated from Swartzia polyphylla .
    Dihydrobiochanin A

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