52 Results for "

urinary biomarker

" in MedChemExpress (MCE) Product Catalog:
Products (52)

52 Results for "urinary biomarker" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-111645
CAS No.: 2140-64-9
Purity:  99.31%
Research Areas:  

Cancer

3-Methylcytidine, a urinary nucleoside, can be used as a biomarker of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-113165A
CAS No.: 6920-31-6
Purity:  ≥98.0%
Isobutyryl-L-carnitine chloride is a biomarker. Isobutyryl-L-carnitine chloride is a product of acyl-CoA dehydrogenases involved in fatty acid β-oxidation, and it buffers the mitochondrial acyl-CoA/CoA ratio, oxidizes branched-chain amino acids, and supports the endogenous antioxidant defense system. Isobutyryl-L-carnitine chloride is a plasma biomarker of hepatic OCT1 transporter inhibition. Isobutyryl-L-carnitine chloride is a urinary biomarker of renal cell carcinoma, and its levels are elevated one year after nephrectomy compared with before nephrectomy. Isobutyryl-L-carnitine chloride can be used in research on renal cell carcinoma .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-113165
CAS No.: 25518-49-4
Isobutyryl-L-carnitine is a biomarker. Isobutyryl-L-carnitine is a product of acyl-CoA dehydrogenases involved in fatty acid β-oxidation, and it buffers the mitochondrial acyl-CoA/CoA ratio, oxidizes branched-chain amino acids, and supports the endogenous antioxidant defense system. Isobutyryl-L-carnitine is a plasma biomarker of hepatic OCT1 transporter inhibition. Isobutyryl-L-carnitine is a urinary biomarker of renal cell carcinoma, and its levels are elevated one year after nephrectomy compared with before nephrectomy. Isobutyryl-L-carnitine can be used in research on renal cell carcinoma .
loading...
    loading...
Cat. No.: HY-77641
CAS No.: 16534-24-0
Cinnamoylglycine is a human urinary metabolite and PPG analog. Cinnamoylglycine is a conjugate of cinnamic acid and glycine. Cinnamoylglycine is used as a urine marker. Cinnamoylglycine can be used in adipogenic differentiation studies .
loading...
    loading...
Cat. No.: HY-113247
CAS No.: 3588-17-8
Purity:  99.93%
trans-trans-Muconic acid is a urinary metabolite of Benzene. trans-trans-Muconic acid serves as a urinary biomarker for occupational benzene exposure .
loading...
    loading...
Cat. No.: HY-114988
CAS No.: 24769-56-0
Synonyms: tetranor-PGEM
PGE-M (tetranor-PGEM) is a metabolite of Prostaglandin E2 (HY-101952) and also an inflammatory biomarker. Urinary PGE-M is a potential biomarker for detecting advanced colorectal tumors. PGE-M can be used in studies related to colorectal cancer, obesity, aging and breast cancer .
loading...
    loading...
Cat. No.: HY-128387
CAS No.: 513-85-9
Purity:  99.87%
2,3-Butanediol is microbially derived compound that is a discriminating urinary biomarker of Fmo5 -/- mice. 2,3-Butanediol prevents age-related increases in the plasma concentration of cholesterol. 2,3-Butanediol has potential applications in the manufacture of printing inks, perfumes, fumigants, moistening and softening agents, plasticizers, and as a carrier for pharmaceuticals .
loading...
    loading...
Cat. No.: HY-129912
CAS No.: 82414-35-5
Purity:  99.96%
N1,N8-Diacetylspermidine is a diacetylated polyamine metabolite and also a urine biomarker associated with diagnosis, prognosis and disease severity. Urinary levels of N1,N8-Diacetylspermidine increase in breast cancer, colorectal cancer, urogenital malignancies and Parkinson's disease. N1,N8-Diacetylspermidine can be used in studies related to breast cancer, colorectal cancer, urogenital malignancies and Parkinson's disease .
loading...
    loading...
Cat. No.: HY-W019151
CAS No.: 569-31-3
Meconine is the urinary metabolite of Noscapine (HY-13716) and also a phase I metabolite of Bromonoscapine. Meconine can serve as a complementary biomarker in addition to opioid metabolites .
loading...
    loading...
Cat. No.: HY-N10374
CAS No.: 527-06-0
Perseitol is a seven-carbon sugar produced by mature avocado plants. Perseitol can be converted into D-mannoheptulose, serving as an energy-providing compound and a transport carbohydrate. Perseitol may act as a ripening inhibitor during fruit maturation. Perseitol can serve as a urinary biomarker for avocado intake and transaldolase deficiency. Perseitol can be used in studies related to transaldolase deficiency .
loading...
    loading...
Cat. No.: HY-W011168
CAS No.: 13389-03-2
8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and an early biomarker of inflammation-induced oxidative tissue damage. The formation of 8-Bromo-2'-deoxyguanosine precedes that of oxidative and nitrative products, and it can be generated via the MPO-H2O2-Cl --Br - system. 8-Bromo-2'-deoxyguanosine serves as the immunogen for preparing the monoclonal antibody mAb8B3, which can be used to detect early DNA modifications in preclinical models; its urinary level also increases significantly in inflammatory disease models. 8-Bromo-2'-deoxyguanosine can also be produced in the dermis of UV-B irradiated mice, and the extract of Coprinus comatus significantly reduces its level. 8-Bromo-2'-deoxyguanosine finds applications in studies related to inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation .
loading...
    loading...
Cat. No.: HY-134611
CAS No.: 13382-47-3
Synonyms: β-hydroxyethoxyacetic acid; HEAA
Target:  

Drug Metabolite

Research Areas:  

Others

(2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the main urinary metabolite of 1,4-Dioxane. (2-Hydroxyethoxy)acetic acid is a reliable and sensitive shortterm biomarker in urine .
loading...
    loading...
Cat. No.: HY-W015464
CAS No.: 16284-60-9
N-Isovaleroylglycine is a peptidylglycine α-amidating monooxygenase (PAM) inhibitor with a Ki value of 2.0 mM against human hsPAM. N-Isovaleroylglycine undergoes oxidative cleavage by purified rat PAM to produce fatty acid amide and glyoxylic acid. N-Isovaleroylglycine exerts competitive inhibition by binding to hsPAM, blocking the amidation of dansyl-Tyr-Val-Gly. N-Isovaleroylglycine exhibits lowered urinary abundance in MRSA-infected mice, which qualifies it as a non-invasive biomarker. N-Isovaleroylglycine can be used in studies related to Staphylococcus aureus pneumonia and diabetic foot .
loading...
    loading...
Cat. No.: HY-113420
CAS No.: 67910-12-7
Purity:  ≥98.0%
11-Dehydro-thromboxane B2 is a stable terminal metabolite of thromboxane A2 and an agonist of the CRTH2 receptor. 11-Dehydro-TXB2 activates human eosinophils, basophils, and CRTH2-transfected BaF/3 cells through a pertussis toxin-insensitive G protein-PLC pathway, inducing intracellular calcium mobilization, morphological changes, and chemotaxis, but does not affect platelet aggregation. 11-Dehydro-thromboxane B2 is involved in thrombosis and promotes eosinophil recruitment to the lungs in allergic inflammation, and its urinary levels are used to assess the inhibitory effect of Aspirin (HY-14654) on thromboxane production. 11-Dehydro-TXB2 serves as a biomarker for research related to asthma, atopic rhinitis, nephropathy, and coronary artery disease .
loading...
    loading...
Cat. No.: HY-113340
CAS No.: 5657-19-2
Purity:  99.93%
2-Furoylglycine, a urinary metabolite in human, is a putative biomarker for coffee consumption .
loading...
    loading...
Cat. No.: HY-111645R
CAS No.: 2140-64-9
3-Methylcytidine (Standard) is the analytical standard of 3-Methylcytidine. This product is intended for research and analytical applications. 3-Methylcytidine, a urinary nucleoside, can be used as a biomarker of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer .
loading...
    loading...
Cat. No.: HY-W019151R
CAS No.: 569-31-3
Meconine (Standard) is the analytical standard of Meconine (HY-W019151). This product is intended for research and analytical applications. Meconine is the urinary metabolite of Noscapine (HY-13716) and also a phase I metabolite of Bromonoscapine. Meconine can serve as a complementary biomarker in addition to opioid metabolites .
loading...
    loading...
Cat. No.: HY-136410
CAS No.: 146764-24-1
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

4-hydroxy Nonenal Mercapturic Acid is a major urinary metabolite of 4-hydroxy-2-nonenal (4-HNE). 4-hydroxy Nonenal Mercapturic Acid metabolites include reduced alcohols, aldehydes, and carboxylic acids, which further form gamma-lactols and gamma-lactones, resulting in 4-5 final urinary metabolites in vivo. 4-hydroxy Nonenal Mercapturic Acid can be used as a biomarker to assess oxidative stress .
loading...
    loading...
Cat. No.: HY-Y1097S
CAS No.: 1276197-40-0
Synonyms: 2-(Methoxycarbonyl)benzoic acid-d4
Monomethyl phthalate-d4 (2-(Methoxycarbonyl)benzoic acid-d4) is the deuterium labeled Monomethyl phthalate. Monomethyl phthalate is a phthalate metabolite. Monomethyl phthalate acts as a urinary biomarker of phthalates exposure and can be used as a standard for the determination of thyroid cancer and benign nodule .
loading...
    loading...
Cat. No.: HY-W416250
CAS No.: 17680-99-8
p-Cresol glucuronide is a metabolite of p-Cresol (HY-Y0506). p-Cresol glucuronide acts as a TLR4-antagonizing blood-brain barrier protective agent in brain microvascular endothelial cells, and serves as a non-invasive urinary biomarker metabolite in renal cell carcinoma. p-Cresol glucuronide inhibits LPS (HY-D1056)-induced increase in blood-brain barrier permeability and signal response, impairs mitochondrial function, induces oxidative stress and enhances inflammatory responses, depletes intracellular glutathione, and increases cell necrosis. p-Cresol glucuronide can be used in studies related to renal cell carcinoma, chronic kidney disease and heart disease .
loading...
    loading...