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Cat. No.: HY-134611

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(2-Hydroxyethoxy)acetic acid

(Synonyms: β-hydroxyethoxyacetic acid; HEAA)

(2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the main urinary metabolite of 1,4-Dioxane. (2-Hydroxyethoxy)acetic acid is a reliable and sensitive shortterm biomarker in urine.

For research use only. We do not sell to patients.

CAS No.: 13382-47-3
Formula: C₄H₈O₄
Molecular Weight:120.10

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

(2-Hydroxyethoxy)acetic acid Chemical Structure

CAS No.: 13382-47-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

(2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the main urinary metabolite of 1,4-Dioxane. (2-Hydroxyethoxy)acetic acid is a reliable and sensitive shortterm biomarker in urine^[1].

In Vitro

(2-Hydroxyethoxy)acetic acid (HEAA) exists in a pH-dependent equilibrium with the cyclic lactone dioxan-2-one, whereby the open-chain form of (2-Hydroxyethoxy)acetic acid is found to be stable under acidic conditions^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

The main metabolic pathway of 1,4-Dioxane is oxidized by cytochrome P450 monooxygenase to (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid; HEAA), which is then rapidly excreted in urine^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 13382-47-3
Molecular Weight 120.10
Formula C₄H₈O₄
SMILES

O=C(O)COCCO
Synonyms

β-hydroxyethoxyacetic acid; HEAA
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Elisabeth Eckert, et al. Reliable quantitation of β-hydroxyethoxyacetic acid in human urine by an isotope-dilution GC-MS procedure. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Sep 15;935:80-4. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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