2. Immunology/Inflammation
  3. Interleukin Related
  4. Tezepelumab (anti-TSLP)

Tezepelumab (anti-TSLP)  (Synonyms: AMG 157 (anti-TSLP); MEDI 19929 (anti-TSLP); Tezepelumab-ekko (anti-TSLP))

Cat. No.: HY-P99366A Pureza: ≥99.0%
COA
SDS
Technical Support

Tezepelumab (anti-TSLP) is human monoclonal antibody (IgG2λ) that binds specifically to TSLP, blocking it from interacting with its heterodimeric receptor. Tezepelumab can be used for the research of severe, uncontrolled asthma.

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No. CAS : 1572943-04-4

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Tezepelumab (anti-TSLP) Recomendaciones destacadas:

Tezepelumab (anti-TSLP) Related Antibodies

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IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22 IL-18

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Descripciòn

Tezepelumab (anti-TSLP) is human monoclonal antibody (IgG2λ) that binds specifically to TSLP, blocking it from interacting with its heterodimeric receptor. Tezepelumab can be used for the research of severe, uncontrolled asthma[1].

Isotype

Human IgG2 lambda
Recommend Isotype Controls
Species Reactivity

Human
IC50 & Target

TSLP
In Vitro

Tezepelumab (anti-TSLP) blocks thymic stromal lymphopoietin, an epithelial-cell-derived cytokine implicated in the pathogenesis of asthma[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tezepelumab (anti-TSLP) Related Antibodies
Ensayo clínico
Gene ID

85480  [NCBI]

Accession

Q969D9-1
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Peso molecular

144.6 kDa

No. CAS
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Tezepelumab (anti-TSLP)]
Envío

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG2 lambda
Biological Activity
  • Immobilized TSLP-ECD-GSV0-His can bind Tezepelumab. The EC50 for this effect is 51.8 ng/mL.
Pureza y Documentación

Purity: ≥99.0%

SDS (252 KB)

COA (232 KB) SDS-PAGE (66 KB) SEC-HPLC (122 KB)

Inhibitory Antibodies User Guide (603 KB)
Referencias
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Tezepelumab (anti-TSLP) Related Classifications

  • Calculadora de molaridad

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tezepelumab (anti-TSLP)1572943-04-4AMG 157 (anti-TSLP) MEDI 19929 (anti-TSLP) Tezepelumab-ekko (anti-TSLP)Interleukin RelatedILTSLPasthmaInhibitorinhibitorinhibit

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Nombre del producto:
Tezepelumab (anti-TSLP)
Cat. No.:
HY-P99366A
Cantidad:
MCE Japan Authorized Agent:

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