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  4. UDP-glucuronic acid trisodium

UDP-glucuronic acid (trisodium)  (Synonyms: ウリジン-5'-ジホスホグルクロン酸三ナトリウム)

製品番号: HY-N7033 純度: 99.87%
COA 取扱説明書 Technical Support

UDP-​glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, ranging from mammalian glycosaminoglycans and plant cell wall polysaccharides to bacterial capsule glycoglycerolipids.

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UDP-glucuronic acid trisodium

UDP-glucuronic acid (trisodium) 構造式

CAS 番号 : 63700-19-6

容量 価格（税別） 在庫状況 数量
>無料サンプル (0.1 - 0.2 mg)   今すぐ申し込む  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 80 在庫あり
Solution
10 mM * 1 mL in DMSO USD 80 在庫あり
Solid
5 mg $56 在庫あり
10 mg $90 在庫あり
25 mg $165 在庫あり
50 mg $265 在庫あり
100 mg $420 在庫あり
250 mg $840 在庫あり
500 mg $1302 在庫あり
1 g $2000 在庫あり
5 g   お問い合わせ  
10 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Other Forms of UDP-glucuronic acid trisodium:

UDP-glucuronic acid (trisodium) 関連抗体

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製品説明

UDP-​glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, ranging from mammalian glycosaminoglycans and plant cell wall polysaccharides to bacterial capsule glycoglycerolipids.

体外実験

UDP-glucuronic acid trisodium (0.5-1 mM, 24 h) promotes the migration of liver cancer cells Huh7, SK-Hep1 and SNU449 through induction of EMT process[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

UDP-glucuronic acid (trisodium) 関連抗体

Cell Migration Assay [2]

Cell Line: Huh7, SK-Hep1 and SNU449
Concentration: 0.5-1 mM
Incubation Time: 24 h
Result: Induced cell migration.

Immunofluorescence[2]

Cell Line: Huh7 and SNU449
Concentration: 0.5 mM
Incubation Time: 24 h
Result: Decreased level of E-cadherin, increased level of vimentin.
分子量

646.23

分子式

C15H19N2Na3O18P2
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]1[C@@H](C(O[Na])=O)O[C@H](OP(OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C=CC(NC3=O)=O)O2)(O[Na])=O)(O[Na])=O)[C@H](O)[C@H]1O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外: 

H2O : ≥ 100 mg/mL (154.74 mM)

DMSO : 20 mg/mL (30.95 mM; ultrasonic and warming and heat to 50°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5474 mL 7.7372 mL 15.4744 mL
5 mM 0.3095 mL 1.5474 mL 3.0949 mL
10 mM 0.1547 mL 0.7737 mL 1.5474 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

体内:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2 mg/mL (3.09 mM); Clear solution

    This protocol yields a clear solution of ≥ 2 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2 mg/mL (3.09 mM); Clear solution

    This protocol yields a clear solution of ≥ 2 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 16.67 mg/mL (25.80 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

純度: 99.87%

COA (255 KB) HNMR (220 KB) RP-HPLC (259 KB) LCMS (94 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 1.5474 mL 7.7372 mL 15.4744 mL 38.6859 mL
5 mM 0.3095 mL 1.5474 mL 3.0949 mL 7.7372 mL
10 mM 0.1547 mL 0.7737 mL 1.5474 mL 3.8686 mL
15 mM 0.1032 mL 0.5158 mL 1.0316 mL 2.5791 mL
20 mM 0.0774 mL 0.3869 mL 0.7737 mL 1.9343 mL
25 mM 0.0619 mL 0.3095 mL 0.6190 mL 1.5474 mL
30 mM 0.0516 mL 0.2579 mL 0.5158 mL 1.2895 mL
H2O 40 mM 0.0387 mL 0.1934 mL 0.3869 mL 0.9671 mL
50 mM 0.0309 mL 0.1547 mL 0.3095 mL 0.7737 mL
60 mM 0.0258 mL 0.1290 mL 0.2579 mL 0.6448 mL
80 mM 0.0193 mL 0.0967 mL 0.1934 mL 0.4836 mL
100 mM 0.0155 mL 0.0774 mL 0.1547 mL 0.3869 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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UDP-glucuronic acid trisodium Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UDP-glucuronic acid trisodium63700-19-6Uridine 5'-diphosphoglucuronic acid trisodiumDrug IntermediateDrug IintermediateInhibitorinhibitorinhibit

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製品名:
UDP-glucuronic acid trisodium
製品番号:
HY-N7033
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