Uridine diphosphate glucuronic acid
Based on 1 Customer Validation
Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a glucuronic acid donor. Uridine diphosphate glucuronic acid transfers its glucuronic acid moiety to acceptor molecules, thereby forming "ether" glucuronides, while being converted into uridine 5'-pyrophosphate. Uridine diphosphate glucuronic acid serves as a substrate for Arabidopsis UDP-GlcA 4-epimerase 1, and undergoes reversible 4-epimerization to generate UDP-α-D-galacturonic acid.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 2616-64-0
- Formula: C15H22N2O18P2
- Molecular Weight:580.29
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Storage:
-80°C
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
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Human Endogenous Metabolite |
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Cell Line
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Type | Value | Description | References |
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| COS-7 | EC50 |
0.37 μM
Compound: 15
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Agonist activity at human P2Y14 receptor expressed in human COS7 cells
Agonist activity at human P2Y14 receptor expressed in human COS7 cells
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[PMID: 19502066] |
| COS-7 | EC50 |
0.37 μM
Compound: 3
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Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysis
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysis
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[PMID: 17407275] |
Uridine diphosphate glucuronic acid (1 mM; 30 min) acts as the active substrate for recombinant truncated Arabidopsis AtUGlcAE1Δ1-64[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2616-64-0
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Appearance Solid
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Molecular Weight 580.29
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Formula C15H22N2O18P2
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Color White to off-white
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SMILES
O[C@@H]1[C@@H](C(O)=O)O[C@H](OP(OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C=CC(NC3=O)=O)O2)(O)=O)(O)=O)[C@H](O)[C@H]1O
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Synonyms
UDP-α-D-glucuronic acid
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Initial Source
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Shipping
Shipping with dry ice.
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Storage
-80°C
Purity & Documentation
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Data Sheet (271 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. DUTTON GJ. Uridine diphosphate glucuronic acid as glucuronyl donor in the synthesis of ester, aliphatic and steroid glucuronides. Biochem J. 1956 Dec;64(4):693-701. [Content Brief]
[2]. Gu X, et al. The biosynthesis of UDP-galacturonic acid in plants. Functional cloning and characterization of Arabidopsis UDP-D-glucuronic acid 4-epimerase. Plant Physiol. 2004 Dec;136(4):4256-64. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Uridine diphosphate glucuronic acid Related Classifications
HY-125954 Related Classifications
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- Uridine diphosphate glucuronic acid
- 2616-64-0
- UDP-α-D-glucuronic acid
- Endogenous Metabolite
- UDP-α-D-galacturonic acid
- Arabidopsis UDP-GlcA 4-epimerase 1
- cell-surface polysaccharide
- glucuronic acid
- mouse liver microsomal fractions
- mouse liver homogenate
- liver preparations
- mouse kidney homogenates
- uridine 5'-pyrophosphate
- glucuronides
- Inhibitor
- inhibitor
- inhibit