Uridine diphosphate glucuronic acid
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Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a glucuronic acid donor. Uridine diphosphate glucuronic acid transfers its glucuronic acid moiety to acceptor molecules, thereby forming "ether" glucuronides, while being converted into uridine 5'-pyrophosphate. Uridine diphosphate glucuronic acid serves as a substrate for Arabidopsis UDP-GlcA 4-epimerase 1, and undergoes reversible 4-epimerization to generate UDP-α-D-galacturonic acid.
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- Pureté: 98.0%
- CAS No.: 2616-64-0
- Formule: C15H22N2O18P2
- Masse moléculaire:580.29
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Stockage:
-80°C
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Activité biologique
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Human Endogenous Metabolite |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| COS-7 | EC50 |
0.37 μM
Compound: 15
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Agonist activity at human P2Y14 receptor expressed in human COS7 cells
Agonist activity at human P2Y14 receptor expressed in human COS7 cells
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[PMID: 19502066] |
| COS-7 | EC50 |
0.37 μM
Compound: 3
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Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysis
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysis
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[PMID: 17407275] |
Uridine diphosphate glucuronic acid (1 mM; 30 min) acts as the active substrate for recombinant truncated Arabidopsis AtUGlcAE1Δ1-64[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2616-64-0
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Appearance Solid
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Masse moléculaire 580.29
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Formule C15H22N2O18P2
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Color White to off-white
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SMILES
O[C@@H]1[C@@H](C(O)=O)O[C@H](OP(OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C=CC(NC3=O)=O)O2)(O)=O)(O)=O)[C@H](O)[C@H]1O
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Synonyms
UDP-α-D-glucuronic acid
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Initial Source
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Livraison
Shipping with dry ice.
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Stockage
-80°C
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Fiche technique (271 KB)
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- Portuguese - PT (394 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. DUTTON GJ. Uridine diphosphate glucuronic acid as glucuronyl donor in the synthesis of ester, aliphatic and steroid glucuronides. Biochem J. 1956 Dec;64(4):693-701. [Content Brief]
[2]. Gu X, et al. The biosynthesis of UDP-galacturonic acid in plants. Functional cloning and characterization of Arabidopsis UDP-D-glucuronic acid 4-epimerase. Plant Physiol. 2004 Dec;136(4):4256-64. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Uridine diphosphate glucuronic acid Related Classifications
HY-125954 Related Classifications
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- Uridine diphosphate glucuronic acid
- 2616-64-0
- UDP-α-D-glucuronic acid
- Endogenous Metabolite
- UDP-α-D-galacturonic acid
- Arabidopsis UDP-GlcA 4-epimerase 1
- cell-surface polysaccharide
- glucuronic acid
- mouse liver microsomal fractions
- mouse liver homogenate
- liver preparations
- mouse kidney homogenates
- uridine 5'-pyrophosphate
- glucuronides
- Inhibitor
- inhibitor
- inhibit