Uridine diphosphate glucuronic acid  (Synonyms: UDP-α-D-glucuronic acid)

Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a glucuronic acid donor. Uridine diphosphate glucuronic acid transfers its glucuronic acid moiety to acceptor molecules, thereby forming "ether" glucuronides, while being converted into uridine 5'-pyrophosphate. Uridine diphosphate glucuronic acid serves as a substrate for Arabidopsis UDP-GlcA 4-epimerase 1, and undergoes reversible 4-epimerization to generate UDP-α-D-galacturonic acid^[1][2].

Uridine diphosphate glucuronic acid (1 mM; 30 min) acts as the active substrate for recombinant truncated Arabidopsis AtUGlcAE1Δ1-64^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

580.29

C₁₅H₂₂N₂O₁₈P₂

2616-64-0

Solid

White to off-white

O[C@@H]1[C@@H](C(O)=O)O[C@H](OP(OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C=CC(NC3=O)=O)O2)(O)=O)(O)=O)[C@H](O)[C@H]1O

Shipping with dry ice.

-80°C

• [1]. DUTTON GJ. Uridine diphosphate glucuronic acid as glucuronyl donor in the synthesis of ester, aliphatic and steroid glucuronides. Biochem J. 1956 Dec;64(4):693-701.  [Content Brief]

  [2]. Gu X, et al. The biosynthesis of UDP-galacturonic acid in plants. Functional cloning and characterization of Arabidopsis UDP-D-glucuronic acid 4-epimerase. Plant Physiol. 2004 Dec;136(4):4256-64.  [Content Brief]