2. Cell Cycle/DNA Damage
  3. Deubiquitinase
  4. USP7-IN-6

USP7-IN-6 is a potent ubiquitin specific protease 7 (USP7) inhibitor, extracted from patent WO2017212010A1, example 25, has an IC50 of 6.8 nM.

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USP7-IN-6

USP7-IN-6 Chemische Struktur

CAS. Nr. : 2166586-47-4

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USP7-IN-6 Related Antibodies

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Alle Deubiquitinase Isoform-spezifische Produkte anzeigen:

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USP1 USP2 USP4 USP7 USP8 USP10 USP21 USP30 UCHL1 USP11 USP15

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Beschreibung

USP7-IN-6 is a potent ubiquitin specific protease 7 (USP7) inhibitor, extracted from patent WO2017212010A1, example 25, has an IC50 of 6.8 nM[1].

IC50 & Target

IC50: 6.8 nM (USP7)[1]
In Vitro

USP7-IN-6 (example 25) shows cytotoxicity to Z138 tumour cells, with an IC50 1.1 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

USP7-IN-6 Related Antibodies
Molekulargewicht

729.89

Formel

C41H43N7O4S
CAS. Nr.
SMILES

O=C1C2=C(N(C3=CC=C(CO)C=C3)C=C2)N=CN1CC4(O)CCN(C([C@H]5[C@H](C6=CC=CC=C6)CN(CC7=CN=C(C8=CC=C(C)N=C8)S7)CC5)=O)CC4
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
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USP7-IN-6 Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

USP7-IN-62166586-47-4DeubiquitinaseDUBscytotoxicitycellstumorZ138Inhibitorinhibitorinhibit

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