[D-Ala2]leucine-enkephalin

Name: [D-Ala2]leucine-enkephalin
Brand: MedChemExpress
SKU: HY-P0098
Rating: 4.5 (0 reviews)

Cat. No.: HY-P0098 Pureza: 98.92%: Ficha de datos
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[D-Ala2]leucine-enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin analog used to study the signaling pathway of delta opioid receptors.

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[D-Ala2]leucine-enkephalin Estructura química

No. CAS : 64963-01-5

Tamaño	Stock	Cantidad
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	Obtener un presupuesto
200 mg	Obtener un presupuesto

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Based on 1 Customer Validation

Recomendaciones destacadas

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Ver todos los productos específicos de isoformas Opioid Receptor:

Ver todas las isoformas

μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

Actividad biológica
Pureza y Documentación
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Descripciòn

[D-Ala2]leucine-enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin analog used to study the signaling pathway of delta opioid receptors.

IC₅₀ & Target

δ Opioid Receptor/DOR

In Vitro

[D-Ala2]leucine-enkephalin is widely distributed in the human body and possesses extremely vital physiological functions. It exerts unique effects on brain cells, being capable of activating dormant brain cells and facilitating the recovery of sequelae caused by brain damage. It also plays an essential role in immune function, including enhancing the activity of the immune system, T lymphocytes, NK cells and macrophages, exerting antiviral effects, and promoting the secretion of gamma-interferon. Additionally, it participates in immune regulation by stimulating endocrine cell secretion through activated immune cells, thereby influencing the gene regulation and expression functions of DNA.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

569.65

Fòrmula

C₂₉H₃₉N₅O₇

No. CAS

64963-01-5

Appearance

Solid

Color

White to off-white

Sequence

Tyr-{d-Ala}-Gly-Phe-Leu

Sequence Shortening

Y-{d-Ala}-GFL

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad

In Vitro:

H₂O : 50 mg/mL (87.77 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.7555 mL	8.7773 mL	17.5546 mL
5 mM	0.3511 mL	1.7555 mL	3.5109 mL
10 mM	0.1755 mL	0.8777 mL	1.7555 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 50 mg/mL (87.77 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Pureza y Documentación

Purity: 98.92%

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Ficha de datos (245 KB) SDS (393 KB)

COA (245 KB) LCMS (329 KB)

Instrucciones de manejo (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.7555 mL	8.7773 mL	17.5546 mL	43.8866 mL
	5 mM	0.3511 mL	1.7555 mL	3.5109 mL	8.7773 mL
	10 mM	0.1755 mL	0.8777 mL	1.7555 mL	4.3887 mL
	15 mM	0.1170 mL	0.5852 mL	1.1703 mL	2.9258 mL
	20 mM	0.0878 mL	0.4389 mL	0.8777 mL	2.1943 mL
	25 mM	0.0702 mL	0.3511 mL	0.7022 mL	1.7555 mL
	30 mM	0.0585 mL	0.2926 mL	0.5852 mL	1.4629 mL
	40 mM	0.0439 mL	0.2194 mL	0.4389 mL	1.0972 mL
	50 mM	0.0351 mL	0.1755 mL	0.3511 mL	0.8777 mL
	60 mM	0.0293 mL	0.1463 mL	0.2926 mL	0.7314 mL
	80 mM	0.0219 mL	0.1097 mL	0.2194 mL	0.5486 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.