2. Anti-infection Immunology/Inflammation
  3. Bacterial Interleukin Related
  4. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole

1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole (Compound 19) is a carbazole alkaloid that can be isolated from Murraya koenigii. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole exhibits anti-inflammatory and antimicrobial activities. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can inhibit the production of pro-inflammatory cytokines TNF-α and IL-6 . 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole has IC50 values of 10.9 μM and 95 μM for Bacillus cereus and Staphylococcus aureus, respectively. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can be used in the research of inflammatory and infectious diseases.

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1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole

1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole Estructura química

No. CAS : 484678-79-7

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1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole Related Antibodies

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Descripciòn

1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole (Compound 19) is a carbazole alkaloid that can be isolated from Murraya koenigii. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole exhibits anti-inflammatory and antimicrobial activities. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can inhibit the production of pro-inflammatory cytokines TNF-α and IL-6 . 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole has IC50 values of 10.9 μM and 95 μM for Bacillus cereus and Staphylococcus aureus, respectively. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can be used in the research of inflammatory and infectious diseases[1].

IC50 & Target[1]

IL-6

 

Peso molecular

309.36

Fòrmula

C19H19NO3
No. CAS
SMILES

O=CC1=CC(O)=C2NC3=C(C2=C1)C=CC(OC)=C3C/C=C(C)\C
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
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1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole Related Classifications

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Keywords:

1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole484678-79-7BacterialInterleukin RelatedILPBMCsmiceBacillus cereusStaphylococcus aureusEscherichia coliCandida albicansInhibitorinhibitorinhibit

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