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  3. Environmental Pollutants Endogenous Metabolite
  4. Xanthine

Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation.

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CAS. Nr. : 69-89-6

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Based on 8 publication(s) in Google Scholar

Other Forms of Xanthine:

Xanthine Related Antibodies

Top Publications Citing Use of Products

    Xanthine purchased from MedChemExpress. Usage Cited in: Cancer Lett. 2025 Sep 29:634:218069.  [Abstract]

    Xanthine (500–2000 μM; 120 h) caused PC-9 and H1975 cell death in a dose-dependent manner.

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    Beschreibung

    Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation[1][2][3].

    IC50 & Target

    Microbial Metabolite

     

    In Vitro

    Xanthine is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme.

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Xanthine Related Antibodies
    Klinische Studie
    Molekulargewicht

    152.11

    Formel

    C5H4N4O2
    CAS. Nr.
    Appearance

    Solid

    Color

    White to light yellow

    SMILES

    O=C(N1)NC2=C(N=CN2)C1=O
    Structure Classification
    Initial Source
    Versand

    Room temperature in continental US; may vary elsewhere.
    Speicherung
    Powder -20°C 3 years
    4°C 2 years
    In solvent -80°C 6 months
    -20°C 1 month
    Lösungsmittel & Löslichkeit
    In Vitro: 

    1M NaOH : 8.33 mg/mL (54.76 mM; ultrasonic and adjust pH to 11 with NaOH)

    H2O : 5 mg/mL (32.87 mM; ultrasonic and warming and adjust pH to 10 with 1M NaOH and heat to 60°C)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 6.5742 mL 32.8709 mL 65.7419 mL
    5 mM 1.3148 mL 6.5742 mL 13.1484 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molaritätsrechner

    • Verdünnungsrechner

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

    ×
    Volume (start)

    V1

    =
    Concentration (final)

    C2

    ×
    Volume (final)

    V2

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

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    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Reinheit & Dokumentation

    Purity: 99.91%

    SDS (393 KB)

    COA (253 KB) HNMR (111 KB) RP-HPLC (204 KB) LCMS (232 KB)

    Handling Instructions (2659 KB)
    Verweise

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O / 1M NaOH 1 mM 6.5742 mL 32.8709 mL 65.7419 mL 164.3547 mL
    5 mM 1.3148 mL 6.5742 mL 13.1484 mL 32.8709 mL
    10 mM 0.6574 mL 3.2871 mL 6.5742 mL 16.4355 mL
    15 mM 0.4383 mL 2.1914 mL 4.3828 mL 10.9570 mL
    20 mM 0.3287 mL 1.6435 mL 3.2871 mL 8.2177 mL
    25 mM 0.2630 mL 1.3148 mL 2.6297 mL 6.5742 mL
    30 mM 0.2191 mL 1.0957 mL 2.1914 mL 5.4785 mL
    1M NaOH 40 mM 0.1644 mL 0.8218 mL 1.6435 mL 4.1089 mL
    50 mM 0.1315 mL 0.6574 mL 1.3148 mL 3.2871 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    Xanthine Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Xanthine69-89-6Environmental PollutantsEndogenous MetaboliteEnvironmental ContaminantsInhibitorinhibitorinhibit

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