Xanthine-13C,15N2
Based on 1 Customer Validation
Xanthine-13C,15N2 is a 15N-labeled and 13C-labled Xanthine (HY-W017389). Xanthine is a plant alkaloid with mild stimulant activity of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation.
For research use only. We do not sell to patients.
- Purity: 95.64%
- CAS No.: 1262670-81-4
- Formula: C413CH4N215N2O2
- Molecular Weight:155.09
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1262670-81-4
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Unlabeled Cas 69-89-6
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Appearance Solid
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Molecular Weight 155.09
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Formula C413CH4N215N2O2
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Color White to light yellow
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SMILES
O=C1C2=C(N=CN2)[15NH][13C]([15NH]1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
1 M NaOH : 8.33 mg/mL (53.71 mM; ultrasonic and adjust pH to 11 with NaOH)
H2O : 5 mg/mL (32.24 mM; ultrasonic and warming and adjust pH to 10 with 1M NaOH and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-244. [Content Brief]
[2]. Pundir CS, et al. Biosensing methods for xanthine determination: a review. Enzyme Microb Technol. 2014;57:55-62. [Content Brief]
[3]. David A. Taylor, et al. Central Nervous SystemStimulants.
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / 1 M NaOH | 1 mM | 6.4479 mL | 32.2393 mL | 64.4787 mL | 161.1967 mL |
| 5 mM | 1.2896 mL | 6.4479 mL | 12.8957 mL | 32.2393 mL | |
| 10 mM | 0.6448 mL | 3.2239 mL | 6.4479 mL | 16.1197 mL | |
| 15 mM | 0.4299 mL | 2.1493 mL | 4.2986 mL | 10.7464 mL | |
| 20 mM | 0.3224 mL | 1.6120 mL | 3.2239 mL | 8.0598 mL | |
| 25 mM | 0.2579 mL | 1.2896 mL | 2.5791 mL | 6.4479 mL | |
| 30 mM | 0.2149 mL | 1.0746 mL | 2.1493 mL | 5.3732 mL | |
| 1 M NaOH | 40 mM | 0.1612 mL | 0.8060 mL | 1.6120 mL | 4.0299 mL |
| 50 mM | 0.1290 mL | 0.6448 mL | 1.2896 mL | 3.2239 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Xanthine-13C,15N2 Related Classifications
HY-W017389S Related Classifications
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