2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Xanthine

Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation.

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Xanthine Chemical Structure

Xanthine Chemical Structure

CAS No. : 69-89-6

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Based on 3 publication(s) in Google Scholar

Other Forms of Xanthine:

Xanthine Related Antibodies

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Description

Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation[1][2][3].

IC50 & Target

Microbial Metabolite

 

Human Endogenous Metabolite

 

In Vitro

A number of stimulants are derived from Xanthine including caffeine and theobromine. Xanthine is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Xanthine Related Antibodies
Clinical Trial
Molecular Weight

152.11

Formula

C5H4N4O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1)NC2=C(N=CN2)C1=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

1M NaOH : 8.33 mg/mL (54.76 mM; ultrasonic and adjust pH to 11 with NaOH)

H2O : 5 mg/mL (32.87 mM; ultrasonic and warming and adjust pH to 10 with 1M NaOH and heat to 60°C)

DMSO : 3.33 mg/mL (21.89 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.5742 mL 32.8709 mL 65.7419 mL
5 mM 1.3148 mL 6.5742 mL 13.1484 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.91%

COA (253 KB) HNMR (111 KB) RP-HPLC (204 KB) LCMS (232 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O / 1M NaOH 1 mM 6.5742 mL 32.8709 mL 65.7419 mL 164.3547 mL
5 mM 1.3148 mL 6.5742 mL 13.1484 mL 32.8709 mL
10 mM 0.6574 mL 3.2871 mL 6.5742 mL 16.4355 mL
15 mM 0.4383 mL 2.1914 mL 4.3828 mL 10.9570 mL
20 mM 0.3287 mL 1.6435 mL 3.2871 mL 8.2177 mL
H2O / 1M NaOH 25 mM 0.2630 mL 1.3148 mL 2.6297 mL 6.5742 mL
30 mM 0.2191 mL 1.0957 mL 2.1914 mL 5.4785 mL
1M NaOH 40 mM 0.1644 mL 0.8218 mL 1.6435 mL 4.1089 mL
50 mM 0.1315 mL 0.6574 mL 1.3148 mL 3.2871 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Xanthine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Xanthine69-89-6Endogenous MetaboliteInhibitorinhibitorinhibit

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