1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Guanosine

Guanosine (Synonyms: DL-Guanosine; Vernine)

Cat. No.: HY-N0097 Purity: >98.0%
Handling Instructions

Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond.

For research use only. We do not sell to patients.

Guanosine Chemical Structure

Guanosine Chemical Structure

CAS No. : 118-00-3

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10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
1 g USD 50 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 5 publication(s) in Google Scholar

Top Publications Citing Use of Products

    Guanosine purchased from MCE. Usage Cited in: Molecules. 2019 May 3;24(9). pii: E1723.

    Guanosine supplementation attenuated the anti-FMDV effect of mizoribine. Serial dilutions of guanosine (from 100 to 25 μM) are added to FMDV (100 TCID50 O/MY98/BY/2010)-infected IBRS-2 cells, when treated with 75 μM mizoribine for 48 h. (A) The cell viability of cells and (B) FMDV VP1 levels are analyzed.

    Guanosine purchased from MCE. Usage Cited in: Mol Immunol. 2019 Aug 3;114:226-232.

    The viral VP1 protein and β-actin are detected by western blot. β-actin was used as an internal control. A serial dilution of guanosine (from 100 μM to 25μM) are added to FMDV infected IBRS-2 cells, when treated with 25 μM merimepodib for 48 h. Cell viability and VP1 protein is analysed as described above.
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    Description

    Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond.

    IC50 & Target

    Human Endogenous Metabolite

     

    In Vitro

    Guanosine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction, and intracellular signal transduction (cGMP).

    Molecular Weight

    283.24

    Formula

    C₁₀H₁₃N₅O₅

    CAS No.

    118-00-3

    SMILES
    Shipping

    Room temperature in continental US; may vary elsewhere

    Storage

    4°C, protect from light

    *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

    Purity: >98.0%

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    Product Name:
    Guanosine
    Cat. No.:
    HY-N0097
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