69-89-6
69-89-6
Chemical Structure
Xanthine
- CAS No.: 69-89-6
- Formula:C5H4N4O2
- Molecular Weight:152.11
IUPAC Name: 3,9-dihydro-1H-purine-2,6-dione
InChIKey: LRFVTYWOQMYALW-UHFFFAOYSA-N
SMILES: O=C(N1)NC2=C(N=CN2)C1=O
Biological Activity: Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Xanthine | 98.99% | Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation. | ||||||||||||||||||||
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Xanthine (Standard) | 99.09% | Xanthine (Standard) is the analytical standard of Xanthine. This product is intended for research and analytical applications. Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation. In Vitro: A number of stimulants are derived from Xanthine including caffeine and theobromine. Xanthine is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme. | ||||||||||||||||||||
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Xanthine-13C,15N2 | 95.64% | Xanthine-13C,15N2 is a 15N-labeled and 13C-labled Xanthine (HY-W017389). Xanthine is a plant alkaloid with mild stimulant activity of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation. | ||||||||||||||||||||
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Xanthine-15N2 | 99.35% | Xanthine-15N2 is a 15N-labeled Xanthine (HY-W017389). Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation. | ||||||||||||||||||||
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8-Hydroxyguanine | 90.05% | 8-Hydroxyguanine is a DNA damage product under oxidative stress, which is formed when hydroxyl radicals attack guanine in DNA. 8-Hydroxyguanine induces mutagenesis and leads to a transversion from G to T. 8-Hydroxyguanine is a marker of DNA oxidative damage. | ||||||||||||||||||||
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Oxypurinol | 98.93% | Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout. | ||||||||||||||||||||
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Oxypurinol (Standard) | 98.50% | Oxypurinol (Standard) is the analytical standard of Oxypurinol. This product is intended for research and analytical applications. Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout. | ||||||||||||||||||||
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3-Methylxanthine (Standard) | 99.58% | 3-Methylxanthine (Standard) is the analytical standard of 3-Methylxanthine. This product is intended for research and analytical applications. 3-Methylxanthine is a blood-brain barrier-permeable cyclic GMP phosphodiesterase inhibitor, with an IC50 of 920 μM against guinea pig cyclic GMP phosphodiesterase. 3-Methylxanthine relaxes the spontaneous tension of isolated guinea pig tracheal smooth muscle preparations. Through a DRD1-dependent pathway, 3-Methylxanthine upregulates the expression of γH2AX and activated caspase-3, downregulates the expression of Bcl-2, and enhances Cisplatin-induced apoptosis (apoptosis) in ovarian cancer cells both in vitro and in vivo. 3-Methylxanthine induces clonic convulsions in the central nervous system. 3-Methylxanthine is the major metabolite of Theophylline (HY-B0809). 3-Methylxanthine can be used in studies related to ovarian cancer and neurotoxic convulsions. | ||||||||||||||||||||
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7-Deazaxanthine | 99.72% | 7-Deazaxanthine (7DX) is an inhibitor of thymidine phosphorylase (TPase). 7-Deazaxanthine inhibits TPase reaction in a concentration-dependent manner with an IC50 value of 40 μM. 7-Deazaxanthine also has a significant angiogenesis inhibitory effect. | ||||||||||||||||||||
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1-Methylxanthine (Standard) | ≥98% | 1-Methylxanthine (Standard) is the analytical standard of 1-Methylxanthine. This product is intended for research and analytical applications. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells. | ||||||||||||||||||||
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1-Methylxanthine-13C4,15N3 | 1-Methylxanthine-13C4,15N3 is the 13C-labeled and 15N-labeled 1-Methylxanthine. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells. | |||||||||||||||||||||
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7-Methylxanthine (Standard) | ≥98% | 7-Methylxanthine (Standard) is the analytical standard of 7-Methylxanthine. This product is intended for research and analytical applications. 7-Methylxanthine is an orally active methyl derivative of xanthine and a non-selective adenosine receptor antagonist. 7-Methylxanthine is also one of the purine components of human urinary calculi. 7-Methylxanthine has anti-myopia activity. | ||||||||||||||||||||
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Pteridine-2,4(1H,3H)-dione | 99.86% | Pteridine-2,4 (1H,3H)-dione is a pteridine derivative (xanthopterin) and a sulfur-containing pteridine compound (2,4-dimercaptopyrimidine). Pteridine-2,4 (1H,3H)-dione possesses metal-binding ability, and forms closed-shell (ionic) interactions with palladium via sulfur and nitrogen atoms. Pteridine-2,4 (1H,3H)-dione derivates can be used in studies related to neuroblastoma, glioma and breast cancer. | ||||||||||||||||||||
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8-Azaxanthine monohydrate | 99.40% | 8-Azaxanthine (monohydrate) is a kind of biochemical reagent. | ||||||||||||||||||||
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Oxypurinol-13C,15N2-1 | Oxypurinol-13C,15N2-1 (Oxipurinol-13C,15N2-1) is 15N and 13C labeled Oxypurinol (HY-19657). Oxipurinol, the major active metabolite of Allopurinoll (HY-B0219), is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout. | |||||||||||||||||||||
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Guanine-15N5 | 98% | Guanine-15N5 is 15N labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects. | ||||||||||||||||||||
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References
- [1]. Pundir CS, Devi R. Biosensing methods for xanthine determination: a review. Enzyme Microb Technol. 2014;57:55-62. [Content Brief]
- [2]. David A. Taylor, et al. Central Nervous SystemStimulants.
- [3]. Ashihara H, et al. Xanthine Alkaloids: Occurrence, Biosynthesis, and Function in Plants. Prog Chem Org Nat Prod. 2017;105:1-88. [Content Brief]
