2. Others Apoptosis Anti-infection Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds HSV Hexokinase Apoptosis
  4. 2-Deoxy-D-glucose-d

2-Deoxy-D-glucose-d  (Synonyms: 2-DG-d1; 2-Deoxy-D-arabino-hexose-d1; D-Arabino-2-deoxyhexose-d1)

製品番号: HY-13966S 純度: 98.0%
COA 取扱説明書 Technical Support

2-Deoxy-D-glucose-d is the deuterium labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.

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2-Deoxy-D-glucose-d

2-Deoxy-D-glucose-d 構造式

CAS 番号 : 188004-07-1

容量 価格（税別） 在庫状況 数量
5 mg $55 在庫あり
10 mg $90 在庫あり
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Other Forms of 2-Deoxy-D-glucose-d:

2-Deoxy-D-glucose-d 関連抗体

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製品説明

2-Deoxy-D-glucose-d is the deuterium labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

体外実験

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-Deoxy-D-glucose-d 関連抗体
分子量

165.16

分子式

C6H11DO5
CAS 番号
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

O=C([2H])C[C@@H](O)[C@H](O)[C@H](O)CO
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

H2O : 250 mg/mL (1513.68 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.0547 mL 30.2737 mL 60.5473 mL
5 mM 1.2109 mL 6.0547 mL 12.1095 mL
10 mM 0.6055 mL 3.0274 mL 6.0547 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

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体積 （開始）

V1

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濃度 （終了）

C2

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体積 （終了）

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
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参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.0547 mL 30.2737 mL 60.5473 mL 151.3684 mL
5 mM 1.2109 mL 6.0547 mL 12.1095 mL 30.2737 mL
10 mM 0.6055 mL 3.0274 mL 6.0547 mL 15.1368 mL
15 mM 0.4036 mL 2.0182 mL 4.0365 mL 10.0912 mL
20 mM 0.3027 mL 1.5137 mL 3.0274 mL 7.5684 mL
25 mM 0.2422 mL 1.2109 mL 2.4219 mL 6.0547 mL
30 mM 0.2018 mL 1.0091 mL 2.0182 mL 5.0456 mL
40 mM 0.1514 mL 0.7568 mL 1.5137 mL 3.7842 mL
50 mM 0.1211 mL 0.6055 mL 1.2109 mL 3.0274 mL
60 mM 0.1009 mL 0.5046 mL 1.0091 mL 2.5228 mL
80 mM 0.0757 mL 0.3784 mL 0.7568 mL 1.8921 mL
100 mM 0.0605 mL 0.3027 mL 0.6055 mL 1.5137 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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2-Deoxy-D-glucose-d Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Deoxy-D-glucose-d188004-07-12-DG-d12-Deoxy-D-arabino-hexose-d1D-Arabino-2-deoxyhexose-d1Isotope-Labeled CompoundsHSVHexokinaseApoptosisHerpes simplex virusInhibitorinhibitorinhibit

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