5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione

Art. -Nr.: HY-141555: Data Sheet Handling Instructions
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5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione is a weak inhibitor for snake venom and human recombinant phosphodiesterase 1 with IC₅₀ of 429 and 467 μM. 5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione inhibits mushroom tyrosinase weakly, with K_i of 1.9 μM.

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5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione Chemische Struktur

CAS. Nr. : 333409-31-7

Größe	Verfügbarkeit	Menge
1 mg	Angebot einholen 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
5 mg	Angebot einholen 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
10 mg	Angebot einholen 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
25 mg	Angebot einholen 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 mg	Angebot einholen
100 mg	Angebot einholen

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Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Alle Phosphodiesterase (PDE) Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen

PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

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Beschreibung	5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione is a weak inhibitor for snake venom and human recombinant phosphodiesterase 1 with IC₅₀ of 429 and 467 μM. 5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione inhibits mushroom tyrosinase weakly, with K_i of 1.9 μM^[1]^[2].
Molekulargewicht	244.29
Formel	C₇H₈N₄O₂S₂
CAS. Nr.	333409-31-7
SMILES	S=C1OC(CCCC2=NNC(O2)=S)=NN1
Versand	Room temperature in continental US; may vary elsewhere.
Speicherung	Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation	Data Sheet (268 KB) Handling Instructions (2659 KB)
Verweise	[1]. Khan KM, et al., 1,3,4-Oxadiazole-2(3H)-thione and its analogues: a new class of non-competitive nucleotide pyrophosphatases/phosphodiesterases 1 inhibitors. Bioorg Med Chem. 2009 Nov 15;17(22):7816-22. [Content Brief] [2]. Ghani U, et al., New potent inhibitors of tyrosinase: novel clues to binding of 1,3,4-thiadiazole-2(3H)-thiones, 1,3,4-oxadiazole-2(3H)-thiones, 4-amino-1,2,4-triazole-5(4H)-thiones, and substituted hydrazides to the dicopper active site. Bioorg Med Chem. 2010 Jun 1;18(11):4042-8. [Content Brief]