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  4. Indocyanine green

インドシアニングリーン  (Synonyms: Indocyanine green; IC Green; Foxgreen; Cardiogreen)

製品番号: HY-D0711 純度: 98.29%
COA 取扱説明書 Technical Support

Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography (Ex/Em = 785/813 nm).

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号 : 3599-32-4

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 27 在庫あり
Solution
10 mM * 1 mL in DMSO USD 27 在庫あり
Solid
10 mg $25 在庫あり
25 mg $45 在庫あり
50 mg $70 在庫あり
100 mg $110 在庫あり
500 mg $374 在庫あり
1 g   お問い合わせ  
5 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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カスタマーレビュー

Based on 41 publication(s) in Google Scholar

Other Forms of Indocyanine green:

インドシアニングリーン 関連抗体

Top Publications Citing Use of Products

顧客検証

Cell Imaging/Staining
Cell Proliferation/Viability Assay
Flow Cytometry
RT-PCR
IF

    Indocyanine green purchased from MedChemExpress. Usage Cited in: Bioact Mater. 2025 Apr 29:50:525-539.

    Representative images of Indocyanine green (ICG) (1 mg/mL, 1 h)-uptake and ICG-excretion of Los.

    Indocyanine green purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2023 Oct:196:106939.  [Abstract]

    The cytotoxicity of Indocyanine green (ICG) (0, 0.1, 0.2, 0.5 mM) to macrophages, illustrated by CCK-8 assay

    Indocyanine green purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2023 Oct:196:106939.  [Abstract]

    The Indocyanine green (ICG) uptake by acceptor T24 cells in non-contact coculture models, illustrated by flow

    Indocyanine green purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2023 Oct:196:106939.  [Abstract]

    The intercellular transport of Indocyanine green (ICG) from ICG-load macrophages to GFP-transfected T24 cells in direct coculture models, illustrated by flow cytometry analysis.

    Indocyanine green purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2023 Oct:196:106939.  [Abstract]

    Photothermal therapy (PTT) by Indocyanine green (ICG) (20 μg/mL) induced STING-dependent and STING-independent type I interferon production in macrophages and tumor cells, respectively.

    Indocyanine green purchased from MedChemExpress. Usage Cited in: Int J Mol Med. 2018 Sep;42(3):1273-1282.  [Abstract]

    Fluorescence in nude mice following intragastric administration of PSP and Indocyanine green (ICG) at different time points. PSP, spirulina polysaccharide; NE, nanoemulsion; ICG, indocyanine green.

    • 生物活性

    • 純度とドキュメンテーション

    • 参考文献

    • カスタマーレビュー

    製品説明

    Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography (Ex/Em = 785/813 nm)[1].

    体外実験

    Indocyanine green (Foxgreen)-photodynamic therapy (ICG-PDT) at concentrations 1000 μg/mL, induces the significant expression of BAX in HGF cells; however, the laser irradiation as well as ICG shows no significant effects on the expression of BCL-2 gene[1].
    Guide (The following is the experimental plan we recommend. This plan serves only as a reference guide. The specific operations should be adjusted according to your actual needs.)
    1. Solution preparation[3]
    1.1 Preparation of stock solution
    Solvent: ddH2O
    Concentration: 1?mg/mL.
    1.2 Preparation of working solution
    Dilute to 0.03-10?μM with Tyrode’s solution or other buffers (optimized according to the experiment).
    Note: The working solution should be prepared and used immediately. Keep it away from light.

    2. Tissue staining
    2.1 Experiments are performed on Langendorff-perfused hearts from New Zealand White rabbits.
    2.2 Blebbistatin (20?μM) (HY-13813) and Biacetyl monoxime (5?mM) (HY-Y0413) are added to the perfusate to suppress contractions while allowing electrical activity to continue.
    2.3 The heart is stained by adding increasing concentrations (from 0.03?μM to 10?μM) of the Indocyanine green dye to the perfusate.
    2.4 Optical signals recorded with a spectrometer are collected for periods of 3?sec in duration.

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    インドシアニングリーン 関連抗体
    体内実験

    Description[2].
    Indocyanine green (ICG) can absorb the near IR laser energy and release heat in the dyed tissue. Pulsed laser treatment combined with Indocyanine green causes targeted tumor cell death in neuroblastoma tumor without capsule.
    Indocyanine green injections and application of laser.
    After tumor volume reached 1000 mm3, mice are anesthetized underwent laparotomy to expose the orthotopic neuroblastoma tumor, liver, and kidney; skin over the proximal leg is removed to expose the quadriceps.
    Exposed tumor and organs are treated at multiple locations with a pulse or continuous wave laser (805 nm), or laser application after an injection of 10 μL of 0.857 mg/mL Indocyanine green (ICG).
    Laser exposure is limited to a 3 mm diameter area for 20-120 seconds. Total energy delivered per treatment area is recorded.

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
    分子量

    774.96

    分子式

    C43H47N2NaO6S2
    Emission (Em)

    813
    Excitation (Ex)

    785
    CAS 番号
    Appearance

    Solid

    Color

    Brown to breen

    SMILES

    O=S(CCCC[N+]1=C(/C=C/C=C/C=C/C=C2N(CCCCS(=O)(O[Na])=O)C3=C(C4=CC=CC=C4C=C3)C/2(C)C)C(C)(C)C5=C1C=CC6=CC=CC=C56)([O-])=O
    輸送条件

    Room temperature in continental US; may vary elsewhere.
    保管条件

    4°C, sealed storage, away from moisture and light

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
    溶剤 & 溶解度
    体外: 

    DMSO : 50 mg/mL (64.52 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    H2O : 5 mg/mL (6.45 mM; ultrasonic and warming and heat to 60°C)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.2904 mL 6.4519 mL 12.9039 mL
    5 mM 0.2581 mL 1.2904 mL 2.5808 mL
    10 mM 0.1290 mL 0.6452 mL 1.2904 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始）

    C1

    ×
    体積 （開始）

    V1

    =
    濃度 （終了）

    C2

    ×
    体積 （終了）

    V2

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    純度とドキュメンテーション

    純度: 98.29%

    COA (256 KB) HNMR (311 KB) RP-HPLC (261 KB) MS (69 KB)

    取扱説明書 (2659 KB)
    Dyeing Example
    参考文献

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O / DMSO 1 mM 1.2904 mL 6.4519 mL 12.9039 mL 32.2597 mL
    5 mM 0.2581 mL 1.2904 mL 2.5808 mL 6.4519 mL
    DMSO 10 mM 0.1290 mL 0.6452 mL 1.2904 mL 3.2260 mL
    15 mM 0.0860 mL 0.4301 mL 0.8603 mL 2.1506 mL
    20 mM 0.0645 mL 0.3226 mL 0.6452 mL 1.6130 mL
    25 mM 0.0516 mL 0.2581 mL 0.5162 mL 1.2904 mL
    30 mM 0.0430 mL 0.2151 mL 0.4301 mL 1.0753 mL
    40 mM 0.0323 mL 0.1613 mL 0.3226 mL 0.8065 mL
    50 mM 0.0258 mL 0.1290 mL 0.2581 mL 0.6452 mL
    60 mM 0.0215 mL 0.1075 mL 0.2151 mL 0.5377 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    Indocyanine green Related Classifications

    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    質量   濃度   体積   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Indocyanine green3599-32-4Foxgreen IC Green CardiogreenFluorescent DyeInhibitorinhibitorinhibit

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    製品名:
    Indocyanine green
    製品番号:
    HY-D0711
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