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  4. Indocyanine green

Indocyanine green  (Synonyms: Foxgreen; IC Green; Cardiogreen)

Cat. No.: HY-D0711 Purity: 98.29%
COA
SDS
Handling Instructions Technical Support

Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography (Ex/Em = 785/813 nm).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No. : 3599-32-4

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
500 mg 해외재고보유
1 g   견적 받기  
5 g   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 41 publication(s) in Google Scholar

Other Forms of Indocyanine green:

Indocyanine green Related Antibodies

Top Publications Citing Use of Products

41 Publications Citing Use of MCE Indocyanine green

Cell Imaging/Staining
Cell Proliferation/Viability Assay
Flow Cytometry
RT-PCR
IF

    Indocyanine green purchased from MedChemExpress. Usage Cited in: Bioact Mater. 2025 Apr 29:50:525-539.

    Representative images of Indocyanine green (ICG) (1 mg/mL, 1 h)-uptake and ICG-excretion of Los.

    Indocyanine green purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2023 Oct:196:106939.  [Abstract]

    The cytotoxicity of Indocyanine green (ICG) (0, 0.1, 0.2, 0.5 mM) to macrophages, illustrated by CCK-8 assay

    Indocyanine green purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2023 Oct:196:106939.  [Abstract]

    The Indocyanine green (ICG) uptake by acceptor T24 cells in non-contact coculture models, illustrated by flow

    Indocyanine green purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2023 Oct:196:106939.  [Abstract]

    The intercellular transport of Indocyanine green (ICG) from ICG-load macrophages to GFP-transfected T24 cells in direct coculture models, illustrated by flow cytometry analysis.

    Indocyanine green purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2023 Oct:196:106939.  [Abstract]

    Photothermal therapy (PTT) by Indocyanine green (ICG) (20 μg/mL) induced STING-dependent and STING-independent type I interferon production in macrophages and tumor cells, respectively.

    Indocyanine green purchased from MedChemExpress. Usage Cited in: Int J Mol Med. 2018 Sep;42(3):1273-1282.  [Abstract]

    Fluorescence in nude mice following intragastric administration of PSP and Indocyanine green (ICG) at different time points. PSP, spirulina polysaccharide; NE, nanoemulsion; ICG, indocyanine green.

    • Biological Activity

    • 순도&문서

    • References

    • 고객리뷰

    제품 설명

    Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography (Ex/Em = 785/813 nm)[1].

    In Vitro

    Indocyanine green (Foxgreen)-photodynamic therapy (ICG-PDT) at concentrations 1000 μg/mL, induces the significant expression of BAX in HGF cells; however, the laser irradiation as well as ICG shows no significant effects on the expression of BCL-2 gene[1].
    Guide (The following is the experimental plan we recommend. This plan serves only as a reference guide. The specific operations should be adjusted according to your actual needs.)
    1. Solution preparation[3]
    1.1 Preparation of stock solution
    Solvent: ddH2O
    Concentration: 1?mg/mL.
    1.2 Preparation of working solution
    Dilute to 0.03-10?μM with Tyrode’s solution or other buffers (optimized according to the experiment).
    Note: The working solution should be prepared and used immediately. Keep it away from light.

    2. Tissue staining
    2.1 Experiments are performed on Langendorff-perfused hearts from New Zealand White rabbits.
    2.2 Blebbistatin (20?μM) (HY-13813) and Biacetyl monoxime (5?mM) (HY-Y0413) are added to the perfusate to suppress contractions while allowing electrical activity to continue.
    2.3 The heart is stained by adding increasing concentrations (from 0.03?μM to 10?μM) of the Indocyanine green dye to the perfusate.
    2.4 Optical signals recorded with a spectrometer are collected for periods of 3?sec in duration.

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Indocyanine green Related Antibodies
    In Vivo

    Description[2].
    Indocyanine green (ICG) can absorb the near IR laser energy and release heat in the dyed tissue. Pulsed laser treatment combined with Indocyanine green causes targeted tumor cell death in neuroblastoma tumor without capsule.
    Indocyanine green injections and application of laser.
    After tumor volume reached 1000 mm3, mice are anesthetized underwent laparotomy to expose the orthotopic neuroblastoma tumor, liver, and kidney; skin over the proximal leg is removed to expose the quadriceps.
    Exposed tumor and organs are treated at multiple locations with a pulse or continuous wave laser (805 nm), or laser application after an injection of 10 μL of 0.857 mg/mL Indocyanine green (ICG).
    Laser exposure is limited to a 3 mm diameter area for 20-120 seconds. Total energy delivered per treatment area is recorded.

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
    분자량

    774.96

    화학식

    C43H47N2NaO6S2
    CAS No.
    Appearance

    Solid

    Color

    Brown to breen

    Emission (Em)

    813
    Excitation (Ex)

    785
    SMILES

    O=S(CCCC[N+]1=C(/C=C/C=C/C=C/C=C2N(CCCCS(=O)(O[Na])=O)C3=C(C4=CC=CC=C4C=C3)C/2(C)C)C(C)(C)C5=C1C=CC6=CC=CC=C56)([O-])=O
    선적

    Room temperature in continental US; may vary elsewhere.
    보관

    4°C, sealed storage, away from moisture and light

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

    용액&용해도
    In Vitro: 

    DMSO : 50 mg/mL (64.52 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    H2O : 5 mg/mL (6.45 mM; ultrasonic and warming and heat to 60°C)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.2904 mL 6.4519 mL 12.9039 mL
    5 mM 0.2581 mL 1.2904 mL 2.5808 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • 몰농도 계산기

    • 농도 희석 계산기

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

    ×
    Volume (start)

    V1

    =
    Concentration (final)

    C2

    ×
    Volume (final)

    V2

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    순도&문서

    Purity: 98.29%

    SDS (394 KB)

    COA (256 KB) HNMR (311 KB) RP-HPLC (261 KB) MS (69 KB)

    Handling Instructions (2659 KB)
    Dyeing Example
    References

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O / DMSO 1 mM 1.2904 mL 6.4519 mL 12.9039 mL 32.2597 mL
    5 mM 0.2581 mL 1.2904 mL 2.5808 mL 6.4519 mL
    DMSO 10 mM 0.1290 mL 0.6452 mL 1.2904 mL 3.2260 mL
    15 mM 0.0860 mL 0.4301 mL 0.8603 mL 2.1506 mL
    20 mM 0.0645 mL 0.3226 mL 0.6452 mL 1.6130 mL
    25 mM 0.0516 mL 0.2581 mL 0.5162 mL 1.2904 mL
    30 mM 0.0430 mL 0.2151 mL 0.4301 mL 1.0753 mL
    40 mM 0.0323 mL 0.1613 mL 0.3226 mL 0.8065 mL
    50 mM 0.0258 mL 0.1290 mL 0.2581 mL 0.6452 mL
    60 mM 0.0215 mL 0.1075 mL 0.2151 mL 0.5377 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    Indocyanine green Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Indocyanine green3599-32-4Foxgreen IC Green CardiogreenFluorescent DyeInhibitorinhibitorinhibit

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    상품명:
    Indocyanine green
    Cat. No.:
    HY-D0711
    수량:
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