1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Cholesteryl palmitate

Cholesteryl palmitate is the main cholesterol ester found in human blephariol and has been used to form a stable tear film to study amphiphilic block copolymers as surfactants for dry eye syndrome. Cholesteryl palmitate can be used as a predictor of fetal lung maturity. Cholesteryl palmitate can be used as a prognostic biomarker for chronic interstitial pneumonia.

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Cholesteryl palmitate

Cholesteryl palmitate Chemische Struktur

CAS. Nr. : 601-34-3

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Beschreibung

Cholesteryl palmitate is the main cholesterol ester found in human blephariol and has been used to form a stable tear film to study amphiphilic block copolymers as surfactants for dry eye syndrome. Cholesteryl palmitate can be used as a predictor of fetal lung maturity. Cholesteryl palmitate can be used as a prognostic biomarker for chronic interstitial pneumonia[1][2][3][4].

IC50 & Target

Human Endogenous Metabolite

 

In Vivo

Cholesteryl palmitate levels in amniotic fluid are decreased in pregnancies in which infants later developed respiratory distress syndrome and in patients with well-controlled diabetes[2][3].
Cholesteryl palmitate is elevated in bronchoalveolar lavage fluid (BALF) of chronic interstitial pneumonia[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

625.08

Formel

C43H76O2

CAS. Nr.
Appearance

Solid

Color

White to off-white

SMILES

CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(CCCCCCCCCCCCCCC)=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

Structure Classification
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Lösungsmittel & Löslichkeit
In Vitro: 

THF : ≥ 100 mg/mL (159.98 mM)

Ethanol : < 1 mg/mL (insoluble)

H2O : < 0.1 mg/mL (insoluble)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5998 mL 7.9990 mL 15.9980 mL
5 mM 0.3200 mL 1.5998 mL 3.1996 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation

Purity: 98.0%

Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
THF 1 mM 1.5998 mL 7.9990 mL 15.9980 mL 39.9949 mL
5 mM 0.3200 mL 1.5998 mL 3.1996 mL 7.9990 mL
10 mM 0.1600 mL 0.7999 mL 1.5998 mL 3.9995 mL
15 mM 0.1067 mL 0.5333 mL 1.0665 mL 2.6663 mL
20 mM 0.0800 mL 0.3999 mL 0.7999 mL 1.9997 mL
25 mM 0.0640 mL 0.3200 mL 0.6399 mL 1.5998 mL
30 mM 0.0533 mL 0.2666 mL 0.5333 mL 1.3332 mL
40 mM 0.0400 mL 0.2000 mL 0.3999 mL 0.9999 mL
50 mM 0.0320 mL 0.1600 mL 0.3200 mL 0.7999 mL
60 mM 0.0267 mL 0.1333 mL 0.2666 mL 0.6666 mL
80 mM 0.0200 mL 0.1000 mL 0.2000 mL 0.4999 mL
100 mM 0.0160 mL 0.0800 mL 0.1600 mL 0.3999 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Produktname:
Cholesteryl palmitate
Art. -Nr.:
HY-W010708
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