2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. sn-Glycerol 3-phosphate

sn-Glycerol 3-phosphate  (Synonyms: sn-グリセロール3-リン酸 リチウム塩)

製品番号: HY-113128 純度: 98.0%
COA 取扱説明書 Technical Support

sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism.

It is advisable to consider the stable salt form (sn-Glycerol 3-phosphate lithium) that retains the same biological activity.

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sn-Glycerol 3-phosphate

sn-Glycerol 3-phosphate 構造式

CAS 番号 : 17989-41-2

容量 在庫状況
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Other 在庫あり Forms of sn-Glycerol 3-phosphate:

sn-Glycerol 3-phosphate 関連抗体

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製品説明

sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism[1][2].

IC50 & Target

Human Endogenous Metabolite

 

体外実験

The cytosolic GPDH consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP), and the resulting sn-Glycerol 3-phosphate passes through the permeable mitochondrial outer membrane. sn-Glycerol 3-phosphate is reoxidized to DHAP at the outer surface of the inner mitochondrial membrane by the mitochondrial FAD-GPDH, which donates the electrons to the mitochondrial ubiquinone pool. The DHAP is subsequently channeled back to the cytosolic compartment[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

sn-Glycerol 3-phosphate 関連抗体
分子量

172.07

分子式

C3H9O6P
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

O[C@H](CO)COP(O)(O)=O
Structure Classification
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

H2O : 125 mg/mL (726.45 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.8116 mL 29.0579 mL 58.1159 mL
5 mM 1.1623 mL 5.8116 mL 11.6232 mL
10 mM 0.5812 mL 2.9058 mL 5.8116 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

体内:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 25 mg/mL (145.29 mM); Clear solution; Need ultrasonic and warming

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

純度: ≥98.0%

COA (245 KB) Elemental Analysis Report (103 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.8116 mL 29.0579 mL 58.1159 mL 145.2897 mL
5 mM 1.1623 mL 5.8116 mL 11.6232 mL 29.0579 mL
10 mM 0.5812 mL 2.9058 mL 5.8116 mL 14.5290 mL
15 mM 0.3874 mL 1.9372 mL 3.8744 mL 9.6860 mL
20 mM 0.2906 mL 1.4529 mL 2.9058 mL 7.2645 mL
25 mM 0.2325 mL 1.1623 mL 2.3246 mL 5.8116 mL
30 mM 0.1937 mL 0.9686 mL 1.9372 mL 4.8430 mL
40 mM 0.1453 mL 0.7264 mL 1.4529 mL 3.6322 mL
50 mM 0.1162 mL 0.5812 mL 1.1623 mL 2.9058 mL
60 mM 0.0969 mL 0.4843 mL 0.9686 mL 2.4215 mL
80 mM 0.0726 mL 0.3632 mL 0.7264 mL 1.8161 mL
100 mM 0.0581 mL 0.2906 mL 0.5812 mL 1.4529 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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sn-Glycerol 3-phosphate Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

sn-Glycerol 3-phosphate17989-41-2Endogenous MetaboliteInhibitorinhibitorinhibit

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