17989-41-2
17989-41-2
Chemical Structure
sn-Glycerol 3-phosphate
- CAS No.: 17989-41-2
- Formula:C3H9O6P
- Molecular Weight:172.07
IUPAC Name: (R)-2,3-dihydroxypropyl dihydrogen phosphate
InChIKey: AWUCVROLDVIAJX-GSVOUGTGSA-N
SMILES: O[C@H](CO)COP(O)(O)=O
Biological Activity: sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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sn-Glycerol 3-phosphate | 98.0% | sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism. | ||||||||||||||||||||
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sn-Glycerol 3-phosphate-13C disodium | 98.7% | sn-Glycerol 3-phosphate-13C3 disodium is the 13C-labeled sn-Glycerol 3-phosphate disodium. sn-Glycerol 3-phosphate disodium is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis. | ||||||||||||||||||||
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References
- [1]. Frasson D, et al. The sympathetic nervous system regulates the three glycerol-3P generation pathways in white adipose tissue of fasted, diabetic and high-protein diet-fed rats. Metabolism. 2012 Oct;61(10):1473-85. [Content Brief]
- [2]. Shen W, et al. Involvement of a glycerol-3-phosphate dehydrogenase in modulating the NADH/NAD+ ratio provides evidence of a mitochondrial glycerol-3-phosphate shuttle in Arabidopsis. Plant Cell. 2006 Feb;18(2):422-41. [Content Brief]
