2. Anti-infection
  3. Bacterial
  4. Dimethyl sulfone

ジメチルスルホン  (Synonyms: Dimethyl sulfone)

製品番号: HY-Y1314 純度: 99.31%
COA 取扱説明書 Technical Support

Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective.

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Dimethyl sulfone

ジメチルスルホン 構造式

CAS 番号 : 67-71-0

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 27 在庫あり
Solution
10 mM * 1 mL in Water USD 27 在庫あり
Solid
5 g $25 在庫あり
10 g $35 在庫あり
50 g $56 在庫あり
100 g $78 在庫あり
500 g $125 在庫あり
1 kg $175 在庫あり

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 3 publication(s) in Google Scholar

Other Forms of Dimethyl sulfone:

ジメチルスルホン 関連抗体

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製品説明

Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective[1][2][3].

IC50 & Target

Microbial Metabolite

 

Human Endogenous Metabolite

 

体外実験

Dimethyl sulfone (25 mM/mL for 15.5 μL/mL; 24 h) inhibits the proliferation of cultured bovine choriocapillary endothelial (CCE) cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ジメチルスルホン 関連抗体
体内実験

Dimethyl sulfone (for 0, 0.01, 0.03, 0.1, 0.3 and 1.0 mL; i.p.; single dose) shows neuroprotective effect with significant infarction volume reduction in ischemia rats[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

94.13

分子式

C2H6O2S
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

O=S(C)(C)=O
Structure Classification
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Store at room temperature 3 years

*In solvent : -80°C, 6 months; -20°C, 1 month (Store at room temperature 3 years)
溶剤 & 溶解度
体外: 

H2O : 50 mg/mL (531.18 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 10.6236 mL 53.1180 mL 106.2361 mL
5 mM 2.1247 mL 10.6236 mL 21.2472 mL
10 mM 1.0624 mL 5.3118 mL 10.6236 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

純度: 99.31%

COA (247 KB) HNMR (112 KB) GC (257 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 10.6236 mL 53.1180 mL 106.2361 mL 265.5901 mL
5 mM 2.1247 mL 10.6236 mL 21.2472 mL 53.1180 mL
10 mM 1.0624 mL 5.3118 mL 10.6236 mL 26.5590 mL
15 mM 0.7082 mL 3.5412 mL 7.0824 mL 17.7060 mL
20 mM 0.5312 mL 2.6559 mL 5.3118 mL 13.2795 mL
25 mM 0.4249 mL 2.1247 mL 4.2494 mL 10.6236 mL
30 mM 0.3541 mL 1.7706 mL 3.5412 mL 8.8530 mL
40 mM 0.2656 mL 1.3280 mL 2.6559 mL 6.6398 mL
50 mM 0.2125 mL 1.0624 mL 2.1247 mL 5.3118 mL
60 mM 0.1771 mL 0.8853 mL 1.7706 mL 4.4265 mL
80 mM 0.1328 mL 0.6640 mL 1.3280 mL 3.3199 mL
100 mM 0.1062 mL 0.5312 mL 1.0624 mL 2.6559 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dimethyl sulfone Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dimethyl sulfone67-71-0Bacterialantiinflammatoryantioxidantlocal anesthetic effectneuroprotectiveInhibitorinhibitorinhibit

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