NGR peptide Trifluoroacetate

Name: NGR peptide Trifluoroacetate
Brand: MedChemExpress
SKU: HY-P1043A
Rating: 4.5 (1 reviews)

製品番号: HY-P1043A 純度: 98.91%: Data Sheet SDS COA 取扱説明書
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NGR peptide Trifluoroacetatecontaining the Asn-Gly-Arg (NGR) motif. NGR peptide Trifluoroacetate binds to APN/CD13. NGR peptide Trifluoroacetate is directly conjugated to imaging agents that can be used for tumor imaging.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

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NGR peptide Trifluoroacetate 構造式

容量	価格（税別）	在庫状況	数量
5 mg	$90	在庫あり	Estimated Time of Arrival: December 31
10 mg	$140	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Other Forms of NGR peptide Trifluoroacetate:

NGR peptide 在庫あり

顧客検証

•Adv Mater. 2024 Apr 21:e2313097. [Abstract]

Aminopeptidase アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

CD13 LTA4H

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

IC₅₀ & Target^[1]^[2]

CD13

体内実験

NGR peptide Trifluoroacetate (20 mg/kg; i.v.) can be used as a potential SPECT agent for imaging and early diagnosis of tumor^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	4-6 weeks, BALB/c nude mice (HepG2 tumor model)^[2]
Dosage:	20 mg/kg
Administration:	I.v.
Result:	Blocked the tumor uptake for 99mTc-NGR.

分子量

722.72

分子式

C₂₂H₃₇F₃N₁₀O₁₀S₂

Appearance

Solid

Color

White to off-white

Sequence

Cys-Asn-Gly-Arg-Cys-Gly

Sequence Shortening

CNGRCG

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Sealed storage, away from moisture
Powder	-80°C	2 years
	-20°C	1 year
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

H₂O : ≥ 100 mg/mL (138.37 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.3837 mL	6.9183 mL	13.8366 mL
5 mM	0.2767 mL	1.3837 mL	2.7673 mL
10 mM	0.1384 mL	0.6918 mL	1.3837 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

体内:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (138.37 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 98.91%

Select Batch:

データシート (278 KB) SDS (252 KB)

COA (255 KB) RP-HPLC (254 KB) MS (72 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Wang RE, et al. Development of NGR peptide-based agents for tumor imaging. Am J Nucl Med Mol Imaging. 2011;1(1):36-46. [Content Brief]

[2]. Ma W, et al. Biodistribution and SPECT imaging study of (99m)Tc labeling NGR peptide in nude mice bearing human HepG2 hepatoma. Biomed Res Int. 2014;2014:618096. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.3837 mL	6.9183 mL	13.8366 mL	34.5915 mL
	5 mM	0.2767 mL	1.3837 mL	2.7673 mL	6.9183 mL
	10 mM	0.1384 mL	0.6918 mL	1.3837 mL	3.4592 mL
	15 mM	0.0922 mL	0.4612 mL	0.9224 mL	2.3061 mL
	20 mM	0.0692 mL	0.3459 mL	0.6918 mL	1.7296 mL
	25 mM	0.0553 mL	0.2767 mL	0.5535 mL	1.3837 mL
	30 mM	0.0461 mL	0.2306 mL	0.4612 mL	1.1531 mL
	40 mM	0.0346 mL	0.1730 mL	0.3459 mL	0.8648 mL
	50 mM	0.0277 mL	0.1384 mL	0.2767 mL	0.6918 mL
	60 mM	0.0231 mL	0.1153 mL	0.2306 mL	0.5765 mL
	80 mM	0.0173 mL	0.0865 mL	0.1730 mL	0.4324 mL
	100 mM	0.0138 mL	0.0692 mL	0.1384 mL	0.3459 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.