1. Infection

Infection

Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P99214
    Panobacumab 885053-97-4 98.24%
    Panobacumab (KBPA101) is a fully human IgM/κ monoclonal antibody generated by immortalizing human B lymphocytes against the LPS O polysaccharide of serotype O11 of P. aeruginosa.
    Panobacumab
  • HY-P99693
    Lenvervimab 2055006-79-4 ≥99%
    Lenvervimab (GC1102) is a IgG1-type recombinant human hepatitis B Immunoglobulin. Lenvervimab can be used for research of hepatitis B virus infection.
    Lenvervimab
  • HY-P99999
    Anti-Mouse CD4 Antibody (YTS 191)
    Anti-Mouse CD4 Antibody (YTS 191) is anti-mouse CD4 IgG2b antibody inhibitor derived from host Rat.
    Anti-Mouse CD4 Antibody (YTS 191)
  • HY-U00160
    SP187 615253-61-7 99.30%
    SP187 is a host-targeted iminosugar with activity against filovirus infections in vitro and in vivo. SP187 is active against influenza and dengue in vivo.
    SP187
  • HY-117411A
    Coblopasvir dihydrochloride 1966138-53-3 99.19%
    Coblopasvir (KW-136) dihydrochloride is a pangenotypic non-structural protein 5A (NS5A) inhibitor. Coblopasvir dihydrochloride can be used for research of chronic hepatitis C virus infection.
    Coblopasvir dihydrochloride
  • HY-123475A
    Sisunatovir hydrochloride 1903763-83-6 98.61%
    Sisunatovir (RV521) hydrochloride is a potent and orally active respiratory syncytial virus (RSV) inhibitor with IC50 values of 1.4, 1.0 nM for RSV A, RSV B, respectively. Sisunatovir hydrochloride inhibits RSV infection and reduces virus titers in the lungs of mice.
    Sisunatovir hydrochloride
  • HY-A0281S
    4-Phenylbutyric acid-d11 358730-86-6 99.30%
    4-Phenylbutyric acid-d11 is the deuterium labeled 4-Phenylbutyric acid. 4-Phenylbutyric acid (4-PBA) is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research.
    4-Phenylbutyric acid-d11
  • HY-B0535S
    Ethambutol-d4 1129526-19-7 98.12%
    Ethambutol-d4 is the deuterium labeled Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.
    Ethambutol-d4
  • HY-12607
    ML251 1486482-16-9 99.62%
    ML251, a potent nanomolar T. brucei and T. cruzi phosphofructokinase (PFK) inhibitor, inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite.
    ML251
  • HY-13784
    Pirodavir 124436-59-5 98.41%
    Pirodavir is a potent, broad-spectrum picornavirus inhibitor, and is highly active against both group A and group B rhinovirus serotypes. Pirodavir is very potent in a virus yield reduction assay (IC90=2.3 nM).
    Pirodavir
  • HY-13833
    Endochin 354155-51-4 99.41%
    Endochin is an antimalarial agent. Endochin inhibits T.gondii with an IC50 of 0.003 nM. Endochin is also active against experimental toxoplasmosis.
    Endochin
  • HY-14987
    AX20017 329221-38-7 99.69%
    AX20017 is a small-molecule protein kinase G (PknG) inhibitor with an IC50 of 0.39 μM.
    AX20017
  • HY-15297
    Vesnarinone 81840-15-5 98.52%
    Vesnarinone (OPC-8212) is an orally active phosphodiesterase 3 (PDE3) inhibitor. Vesnarinone can increase in calcium flux and decrease in potassium flux. Vesnarinone shows dose-dependent positive inotropic activity. Vesnarinone can be used in heart failure research.
    Vesnarinone
  • HY-16952
    Bepridil 64706-54-3 99.93%
    Bepridil ((±)-Bepridil) is a calcium channel blocking agent used as antiarrhythmic agent. Bepridil inhibits both calcium and sodium currents, has research potential in certain ischemia-induced ventricular arrhythmias. Bepridil also has strong inhibition of SARS-CoV-2 from entry and replication inside Vero E6 and A549 cells.
    Bepridil
  • HY-18076
    LPA1 receptor antagonist 1 1396006-71-5 99.13%
    LPA1 receptor antagonist 1 is a highly selective Lysophosphatidic Acid receptor-1 (LPA1) antagonist with an IC50 of 25 nM.
    LPA1 receptor antagonist 1
  • HY-19364
    Ferroquine 185055-67-8 99.55%
    Ferroquine (Ferrochloroquine), a ferrocenyl analogue of Chloroquine, is an antimalarial agent. Ferroquine shows parasiticidal effect on Plasmodium by inducing oxidative stress and the subsequent destruction of the membrane.
    Ferroquine
  • HY-21200
    Perfluoroheptanesulfonic acid 375-92-8
    Perfluoroheptanesulfonic acid (1-Perfluoroheptanesulfonic acid; Perfluoroheptanesulphonic acid) is a perfluoroalkyl substance (PFAS). PFHpS can induce malformations in zebrafish larvae (EC50=168.1 μM). It has also been found in landfill leachate, and fetal exposure to PFHpS can lead to reduced birth weight.
    Perfluoroheptanesulfonic acid
  • HY-41344
    Ganciclovir mono-O-acetate 88110-89-8 98.00%
    Ganciclovir mono-O-acetate is a derivative of Ganciclovir. Ganciclovir, a nucleoside analogue, is an orally active antiviral agent with activity against CMV.
    Ganciclovir mono-O-acetate
  • HY-44358
    Remdesivir nucleoside monophosphate 1911578-74-9 99.87%
    Remdesivir nucleoside monophosphate is a metabolite of Remdesivir (HY-104077).
    Remdesivir nucleoside monophosphate
  • HY-60325
    2-Amino-4-chloropyridine 19798-80-2 99.92%
    2-Amino-4-chloropyridine is a key intermediate. 2-Amino-4-chloropyridine derivatives exhibit antibacterial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi.
    2-Amino-4-chloropyridine
Cat. No. Product Name / Synonyms Application Reactivity