Remdesivir nucleoside monophosphate

Cat. No.: HY-44358 Purity: 99.98%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Remdesivir nucleoside monophosphate is a metabolite of Remdesivir. Remdesivir is a nucleoside analogue with effective antiviral activity against SARS-CoV and MERS-CoV.

For research use only. We do not sell to patients.

Remdesivir nucleoside monophosphate Chemical Structure

CAS No. : 1911578-74-9

Size	Price	Stock	Quantity
1 mg	USD 522	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 1200	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 2 publication(s) in Google Scholar

2 Publications Citing Use of MCE Remdesivir nucleoside monophosphate

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Remdesivir nucleoside monophosphate is a metabolite of Remdesivir^[1]. Remdesivir is a nucleoside analogue with effective antiviral activity against SARS-CoV and MERS-CoV^[2].

Molecular Weight

371.24

Formula

C₁₂H₁₄N₅O₇P

CAS No.

1911578-74-9

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@@H](O)[C@](C#N)(C2=CC=C3C(N)=NC=NN32)O[C@@H]1COP(O)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL (67.34 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6937 mL	13.4684 mL	26.9368 mL
5 mM	0.5387 mL	2.6937 mL	5.3874 mL
10 mM	0.2694 mL	1.3468 mL	2.6937 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.98%

Select Batch:

Data Sheet (277 KB) SDS (251 KB)

COA (255 KB) RP-HPLC (244 KB)

Handling Instructions (2659 KB)

References

[1]. Byoung Kwon Chun, et al. or treating filoviridae virus infections. US20160122374.

[2]. Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2). pii: e00221-18. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6937 mL	13.4684 mL	26.9368 mL	67.3419 mL
	5 mM	0.5387 mL	2.6937 mL	5.3874 mL	13.4684 mL
	10 mM	0.2694 mL	1.3468 mL	2.6937 mL	6.7342 mL
	15 mM	0.1796 mL	0.8979 mL	1.7958 mL	4.4895 mL
	20 mM	0.1347 mL	0.6734 mL	1.3468 mL	3.3671 mL
	25 mM	0.1077 mL	0.5387 mL	1.0775 mL	2.6937 mL
	30 mM	0.0898 mL	0.4489 mL	0.8979 mL	2.2447 mL
	40 mM	0.0673 mL	0.3367 mL	0.6734 mL	1.6835 mL
	50 mM	0.0539 mL	0.2694 mL	0.5387 mL	1.3468 mL
	60 mM	0.0449 mL	0.2245 mL	0.4489 mL	1.1224 mL