1911578-74-9
1911578-74-9
Chemical Structure
Remdesivir nucleoside monophosphate
- CAS No.: 1911578-74-9
- Formula:C12H14N5O7P
- Molecular Weight:371.24
IUPAC Name: ((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
InChIKey: ZBHOHJWLOOFLMW-LTGWCKQJSA-N
SMILES: O[C@H]1[C@@H](O)[C@](C#N)(C2=CC=C3C(N)=NC=NN32)O[C@@H]1COP(O)(O)=O
Biological Activity: Remdesivir nucleoside monophosphate is a metabolite of Remdesivir (HY-104077)[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Remdesivir nucleoside monophosphate | 99.87% | Remdesivir nucleoside monophosphate is a metabolite of Remdesivir (HY-104077). | ||||||||||||||||||||
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References
- [1]. Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2). pii: e00221-18. [Content Brief]
- [2]. Wang M, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020 Mar;30(3):269-271. [Content Brief]
- [3]. Hu H, et al. Optimization of the Prodrug Moiety of Remdesivir to Improve Lung Exposure/Selectivity and Enhance Anti-SARS-CoV-2 Activity. J Med Chem. 2022 Sep 22;65(18):12044-12054. [Content Brief]
Keywords
