2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P3601
    Brain Derived Basic Fibroblast Growth Factor (1-24) 211362-85-5 98.01%
    Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24) is a synthetic peptide, shows anti-bacterial and anti-HBV activities. Brain Derived Basic Fibroblast Growth Factor (1-24) can be used in infection disease and immune disease research.
    Brain Derived Basic Fibroblast Growth Factor (1-24)
  • HY-P3794
    Glu-Ala-Leu-Phe-Gln-pNA 198551-00-7 98.57%
    Glu-Ala-Leu-Phe-Gln-pNA is a Chiba virus 3C-like protease (CVP) substrate.
    Glu-Ala-Leu-Phe-Gln-pNA
  • HY-P3915
    Esculentin 1A 1350828-38-4 98.85%
    Esculentin 1A is a frog skin-derived antimicrobial peptide (AMP) with potent in vitro anti-Pseudomonas activity.
    Esculentin 1A
  • HY-P4211
    PSM-β 99.53%
    PSM-β is a active peptide , which can be isolated from Staphylococcus epidermidis. PSM-β is an analog of staphylococcal toxins, as well as a termed phenol-soluble modulin. PSM-β has bacteriostatic and poorly hemolytic properties.
    PSM-β
  • HY-P4848
    Dermcidin-1L (human) 478898-18-9 98.81%
    Dermcidin-1L (human) is an antibiotic peptide secreted by sweat glands. Dermcidin-1L (human) has antimicrobial activity. Dermcidin-1L (human) can be used for the research of inflammatory skin disorders.
    Dermcidin-1L (human)
  • HY-P5753
    JB-95 1873323-60-4 98.03%
    JB-95, a β-hairpin macrocyclic peptide, exhibits potent antimicrobial activity against Escherichia coli. JB-95 can selectively disrupt the outer membrane but not the inner membrane of E. coli.
    JB-95
  • HY-P9957
    Raxibacumab 565451-13-0 98.88%
    Raxibacumab (ABthrax) is a human IgG1 monoclonal antibody against Bacillus anthracis protective antigen (PA). Raxibacumab blocks the toxin’s deleterious effects by preventing binding of the protective antigen component of the anthrax toxin to its receptors in host cells, thereby blocking the toxin’s deleterious effects. Raxibacumab can be used for anti-anthrax research.
    Raxibacumab
  • HY-Y0123
    DL-Tyrosine 556-03-6 ≥98.0%
    DL-Tyrosine is an aromatic nonessential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is a precursor for several important neurotransmitters (epinephrine, norepinephrine, dopamine).
    DL-Tyrosine
  • HY-Y0999
    2-Nonanone 821-55-6 99.82%
    2-Nonanone is a ketone compound that inhibits the DnaKJE-ClpB bichaperone de-pendent refolding of heat-inactivated bacterial luciferases. 2-Nonanone interacts with hydrophobic segments of heat-inactivated substrates, and competes with chaperones IbpAB. 2-Nonanone can be used for the research of infection.
    2-Nonanone
  • HY-100679
    Pirlindole 60762-57-4 98.90%
    Pirlindole is a selective and reversible MAO-A inhibitor. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3).
    Pirlindole
  • HY-106784
    Ajoene 92285-01-3 ≥99.0%
    Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities.
    Ajoene
  • HY-107260
    Lucidenic acid D 98665-16-8 99.78%
    Lucidenic acid D is a highly oxidized triterpenoid with anti-inflammatory and antiviral activities. Lucidenic acid D attenuates lipopolysaccharide-induced release of proinflammatory cytokines and nitric oxide, reduces the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), and inhibits skin inflammation. Lucidenic acid D suppresses 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced expression of Epstein-Barr virus (EBV) early antigen and maintains the viability of Raji cells. Lucidenic acid D can be used in studies of cancer chemoprevention.
    Lucidenic acid D
  • HY-107329
    Cefathiamidine 33075-00-2 99.65%
    Cefathiamidine is a first-generation cephalosporin antibacterial agent and is used to treat infections caused by susceptible bacteria. Cefathiamidine exhibits a wide spectrum of antimicrobial activity against bacteria. Cefathiamidine is used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis.
    Cefathiamidine
  • HY-107496
    Imidocarb dipropionate 55750-06-6 99.07%
    Imidocarb dipropionate is a potent antiprotozoal agent. Imidocarb dipropionate is active against the parasite B. bovis with an IC50 of 87 μg/mL.
    Imidocarb dipropionate
  • HY-107634
    CP-20961 35607-20-6 98.34%
    CP-20961 is an interferon inducer. CP-20961 is a potent synthetic non-immunogenic adjuvant that induces arthritis.
    CP-20961
  • HY-107833
    A40926 102961-72-8
    A40926 is a glycopeptide antibiotic that targets the bacterial cell wall peptidoglycan precursor D-alanyl-D-alanine (D-Ala-D-Ala). A40926 irreversibly inhibits cell wall synthesis by competitively binding to this target, and has high bactericidal activity against Gram-positive bacteria (such as Staphylococcus, Streptococcus) and Neisseria gonorrhoeae, with MIC=0.06-2 μg/mL, and is also effective against penicillin-resistant strains. A40926 blocks peptidoglycan cross-linking, destroys cell wall integrity, and causes bacterial lysis and death. A40926 has a fat-soluble fatty acid structure, which can increase serum concentrations and prolong the duration of action (e.g., the terminal half-life in rats is 61.22 h).
    A40926
  • HY-10846S
    Delamanid-d4 2747917-54-8 98.44%
    Delamanid-d4 is the deuterium labeled Delamanid. Delamanid, a newer?mycobacterial cell wall synthesis ?inhibitor, inhibits the synthesisi of mucolic acids.
    Delamanid-d4
  • HY-108569
    nTZDpa 118414-59-8 98.53%
    nTZDpa is an antibiotic. nTZDpa is a PPARG partial agonist. nTZDpa has antibacterial activity. nTZDpa is effective against growing and persistent Staphylococcus aureus by lipid bilayer disruption.
    nTZDpa
  • HY-108818
    XZ426 1638504-52-5 99.81%
    XZ426 is a potent integrase strand transfer inhibitor with anti- HIV activity.
    XZ426
  • HY-111069
    Nifeviroc 934740-33-7 99.39%
    Nifeviroc is an orally active CCR5 antagonist. Nifeviroc is used for the study of HIV type-1 infection.
    Nifeviroc
Cat. No. Product Name / Synonyms Application Reactivity