Brain Derived Basic Fibroblast Growth Factor (1-24)
Based on 1 Customer Validation
Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24) is a synthetic peptide, shows anti-bacterial and anti-HBV activities. Brain Derived Basic Fibroblast Growth Factor (1-24) can be used in infection disease and immune disease research.
For research use only. We do not sell to patients.
- Purity : 98.01%
- CAS No.: 211362-85-5
- Formula: C118H173N31O33
- Molecular Weight:2553.82
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Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Brain Derived Basic Fibroblast Growth Factor (1-24) (10 μg/mL; 12 h) inhibits the growth of Streptococcus pneumoniae[1].
Brain Derived Basic Fibroblast Growth Factor (1-24) (10 μg/mL; 6 d) inhibits HBV replication of HepG2-2.2.15 cells[1].
Brain Derived Basic Fibroblast Growth Factor (1-24) (10 μg/mL; 22 h) inhibits the migration of human endothelial cell[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
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Cell Line:Streptococcus pneumoniae
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Concentration:10 μg/mL
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Incubation Time:12 hours
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Result:Inhibited by 100% the growth of Streptococcus pneumoniae.
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Cell Line:HepG2-2.2.15 cells
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Concentration:10 μg/mL
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Incubation Time:6 days
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Result:Inhibited by 31.4% HBV replication as compared to the virus control infection.
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Cell Line:Human endothelial cells (HUVEC)
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Concentration:10 μg/mL
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Incubation Time:22 hours
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Result:Inhibited by 17% the migration of human endothelial cells
Chemical Information
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CAS No. 211362-85-5
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Appearance Solid
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Molecular Weight 2553.82
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Formula C118H173N31O33
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Color White to off-white
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Synonyms
FGF basic (1-24)
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Sequence Shortening
PALPEDGGSGAFPPGHFKDPKRLY
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (9.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
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Data Sheet (268 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.3916 mL | 1.9579 mL | 3.9157 mL | 9.7893 mL |
| 5 mM | 0.0783 mL | 0.3916 mL | 0.7831 mL | 1.9579 mL |
Brain Derived Basic Fibroblast Growth Factor (1-24) Related Classifications
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