2. Others Metabolic Enzyme/Protease
  3. Environmental Pollutants Endogenous Metabolite
  4. 2-Nonanone

2-Nonanone is a ketone compound that inhibits the DnaKJE-ClpB bichaperone de-pendent refolding of heat-inactivated bacterial luciferases. 2-Nonanone interacts with hydrophobic segments of heat-inactivated substrates, and competes with chaperones IbpAB. 2-Nonanone can be used for the research of infection.

For research use only. We do not sell to patients.

2-Nonanone

2-Nonanone Chemical Structure

CAS No. : 821-55-6

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Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
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Based on 1 publication(s) in Google Scholar

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2-Nonanone Related Antibodies

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Description

2-Nonanone is a ketone compound that inhibits the DnaKJE-ClpB bichaperone de-pendent refolding of heat-inactivated bacterial luciferases. 2-Nonanone interacts with hydrophobic segments of heat-inactivated substrates, and competes with chaperones IbpAB. 2-Nonanone can be used for the research of infection[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

2-Nonanone (2.5μM) decreases the level of refolding of luciferase in E. coli BW25113 ibpAB+ and JW3663 ibpB::kan cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-Nonanone Related Antibodies
Molecular Weight

142.24

Formula

C9H18O
CAS No.
Appearance

Liquid (Density: 0.8188 g/cm3)

SMILES

O=C(C)CCCCCCC
Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (1406.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.0304 mL 35.1519 mL 70.3037 mL
5 mM 1.4061 mL 7.0304 mL 14.0607 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

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In Vivo Dissolution Calculator
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Purity & Documentation

Purity: 99.82%

SDS (393 KB)

COA (240 KB) HNMR (129 KB) GC (213 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.0304 mL 35.1519 mL 70.3037 mL 175.7593 mL
5 mM 1.4061 mL 7.0304 mL 14.0607 mL 35.1519 mL
10 mM 0.7030 mL 3.5152 mL 7.0304 mL 17.5759 mL
15 mM 0.4687 mL 2.3435 mL 4.6869 mL 11.7173 mL
20 mM 0.3515 mL 1.7576 mL 3.5152 mL 8.7880 mL
25 mM 0.2812 mL 1.4061 mL 2.8121 mL 7.0304 mL
30 mM 0.2343 mL 1.1717 mL 2.3435 mL 5.8586 mL
40 mM 0.1758 mL 0.8788 mL 1.7576 mL 4.3940 mL
50 mM 0.1406 mL 0.7030 mL 1.4061 mL 3.5152 mL
60 mM 0.1172 mL 0.5859 mL 1.1717 mL 2.9293 mL
80 mM 0.0879 mL 0.4394 mL 0.8788 mL 2.1970 mL
100 mM 0.0703 mL 0.3515 mL 0.7030 mL 1.7576 mL
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2-Nonanone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Nonanone821-55-6Environmental PollutantsEndogenous MetaboliteEnvironmental Contaminantsheat-inactivated substratesEscherichia coli cellschaperones IbpABhydrophobic segmentsDnaKJE-ClpB bichaperone systemInhibitorinhibitorinhibit

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