2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. 상품명 CAS No. Purity 화학구조
  • HY-P10310A
    F9170 TFA 99.70%
    F9170 TFA is an amphipathic peptide with an activity of inactivate HIV-1 virions. F9170 TFA targets the conserved cytoplasmic tail of HIV-1 env and disrupts the integrity of the viral membrane. F9170 TFA is able to cross the blood-brain barrier (BBB).
    F9170 TFA
  • HY-P990123
    Anti-Mouse ICOSL/CD275 Antibody (HK5.3) 98.59%
    Anti-Mouse ICOSL/CD275 Antibody (HK5.3) is an anti-mouse ICOSL/CD275 IgG2a monoclonal antibody. Anti-Mouse ICOSL/CD275 Antibody (HK5.3) can inhibit the adhesion between T cells and endothelial cells. Anti-Mouse ICOSL/CD275 Antibody (HK5.3) can reduce the expansion of tissue resident (TR) Treg cells. Anti-Mouse ICOSL/CD275 Antibody (HK5.3) can be used for researches on inflammation and infection conditions such as influenza virus infection and arthritis.
    Anti-Mouse ICOSL/CD275 Antibody (HK5.3)
  • HY-P990276
    Anti-Mouse CD317/BST2 Antibody (927)
    Anti-Mouse CD317/BST2 Antibody (927) is a rat-derived IgG2b κ type antibody inhibitor, targeting to mouse CD317/BST2. Anti-Mouse CD317/BST2 Antibody (927) can deplete plasmacytoid dendritic cells (pDC). Anti-Mouse CD317/BST2 Antibody (927) can be used for the researches of cancer, infection, inflammation and immunology, such as head and neck squamous cell carcinoma (HNSCC), murine cytomegalovirus (MCMV) infection and asthma.
    Anti-Mouse CD317/BST2 Antibody (927)
  • HY-P991112
    Anti-Mouse CD8α Antibody (YTS169.4) 98.99%
    Anti-Mouse CD8α Antibody (YTS169.4) is an IgG2 monoclonal antibody targeting mouse CD8α. Anti-Mouse CD8α Antibody (YTS169.4) rapidly depletes or downregulates CD8+ T cells in the spleens of Biozzi AB/H mice. Anti-Mouse CD8α Antibody (YTS169.4) is applicable to research related to hepatitis B virus infection. Recommended isotype control: Rat IgG2b kappa, Isotype Control (HY-P990682).
    Anti-Mouse CD8α Antibody (YTS169.4)
  • HY-P991492
    RSM-01
    RSM-01 is a monoclonal antibody targeting site Ø of the pre-fusion F glycoprotein (Fusion glycoprotein F0) of respiratory syncytial virus (RSV). RSM-01 can be used in studies related to RSV infection.
    RSM-01
  • HY-P991674
    Brelovitug 3033337-14-0 99%
    Brelovitug (BJT-778) is a humanized IgG1 neutralizing monoclonal antibody targeting hepatitis B surface antigen (HBsAg). Brelovitug binds with high affinity to HBsAg purified from HBV serotypes ad and ay, with Kd values of 0.22 nM and 0.39 nM, respectively. Brelovitug binds with high affinity to HBsAg of HBV genotypes A, B, C and D, with IC50 values of 0.07, 0.02, 0.02 and 0.07 nM, respectively. Brelovitug can be used in research related to chronic hepatitis B and chronic hepatitis D.
    Brelovitug
  • HY-RS16308
    mt-Co1 Mouse Pre-designed siRNA Set A

    mt-Co1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for mt-Co1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    mt-Co1 Mouse Pre-designed siRNA Set A
  • HY-W001119
    6-Hydroxyindazole 23244-88-4 98%
    6-Hydroxyindazole is an anti-parasite agent with an EC50 of 128.9 μM against intracellular amastigotes of Leishmania amazonensis. 6-Hydroxyindazole can be used in the research of leishmaniasis.
    6-Hydroxyindazole
  • HY-W002297
    (S)-3-Aminoazepan-2-one 21568-87-6
    (S)-3-Aminoazepan-2-one is the structural unit of the antitubercular peptide, serving as the core scaffold of a hexapeptide antibacterial agent. (S)-3-Aminoazepan-2-one is promising for research of tuberculosis.
    (S)-3-Aminoazepan-2-one
  • HY-W004291
    Methyl arachidate 1120-28-1 ≥98.0%
    Methyl arachidate (Methyl icosanoate) is a component of lipid mixtures. Methyl arachidate can be isolated from flowering plants. Methyl arachidate inhibits LTA4H. Methyl arachidate shows no antifeedant activity against Leptinotarsa decemlineata.
    Methyl arachidate
  • HY-W004812
    BOC-(1R,3S)-3-aminocyclopentane carboxylic acid 161660-94-2 ≥98.0%
    BOC-(1R,3S)-3-aminocyclopentane carboxylic acid ((1S,3S)-3-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acid) is a conformationally constrained peptide building block and a key component of SARS-CoV-2 main protease (Mpro) inhibitors. When incorporated into macrocyclic peptides, BOC-(1R,3S)-3-aminocyclopentane carboxylic acid not only helps generate high-affinity Mpro inhibitors by preorganizing the secondary structure of peptides, but also exerts sequence-dependent functional inhibition on the hydrolytic activity of Mpro. BOC-(1R,3S)-3-aminocyclopentane carboxylic is widely used in COVID-19-related research.
    BOC-(1R,3S)-3-aminocyclopentane carboxylic acid
  • HY-W005297
    4,6-Dimethoxysalicylaldehyde 708-76-9 99.96%
    4,6-dimethoxysalicylaldehyde is an antifungal agent. 4,6-dimethoxysalicylaldehyde has considerable activity against C. albicans and slight activity against S. cerevisiae.
    4,6-Dimethoxysalicylaldehyde
  • HY-W009213
    3-Nitrophenyl disulfide 537-91-7 99.23%
    3-Nitrophenyl disulfide (Bis(3-Nitrophenyl) disulfide) is an inhibitor of mannitol-1-phosphate dehydrogenase (M1PDH) with IC50 of 3 μM. 3-Nitrophenyl disulfide has antiparasitic activity.
    3-Nitrophenyl disulfide
  • HY-W011539
    EcMetAP1-IN-1 24683-26-9 99.34%
    EcMetAP1-IN-1 (compound 4) is an inhibitor of Escherichia coli methionine aminopeptidase MetAP1.
    EcMetAP1-IN-1
  • HY-W012267
    2-Bromo-2'-methoxyacetophenone 31949-21-0 ≥98.0%
    2-Bromo-2'-methoxyacetophenone is an irreversible inhibitor for MurA, that inhibits MurA in E. coli with an IC50 of 0.38 μM. 2-Bromo-2'-methoxyacetophenone can be used in antibacterial research for blocking bacterial cell wall synthesis.
    2-Bromo-2'-methoxyacetophenone
  • HY-W013040
    Pyrazine 290-37-9 99.97%
    Pyrazine (1,4-Diazine) is an aromatic nitrogen-containing heterocyclic compound with two nitrogen atoms, and is well known for its electron-deficient property. Pyrazine serves as a key pharmacophore in a variety of drugs, and also acts as the core skeleton of derivatives with anticancer, antimycobacterial, antithrombotic and anti-inflammatory activities.
    Pyrazine
  • HY-W016203
    Phenylpyruvic acid sodium 114-76-1 98.24%
    Phenylpyruvic acid sodium is a endogenous metabolite that participates in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase. Phenylpyruvic acid is a precursor of the antifungal compound phenyllactic acid. Phenylpyruvic acid can improve the antifungal activity of eight lactic acid bacterial strains through the addition into a dedined growth medium. Phenylpyruvic acid demonstrates improved inhibitory activity against fungal bread contaminants Aspergillus niger and Penicillium roqueforti. Phenylpyruvic acid affects enzyme activity of the pentose phosphate pathway involved in the oxidative phase in rat brain homogenates. Phenylpyruvic acid can reduce glucose-6-phosphate dehydrogenase activity.
    Phenylpyruvic acid sodium
  • HY-W016639
    4-Chloroquinaldine 4295-06-1 98%
    4-Chloroquinaldine is an antibacterial agent. 4-Chloroquinaldine is an intermediate.
    4-Chloroquinaldine
  • HY-W018359
    Tolyl diiodomethyl sulfone 20018-09-1 98%
    Tolyl diiodomethyl sulfone is an organic antibacterial agent that does not cause significant changes in the number of resorbed fetuses, the number of dead fetuses, or the body weight of live fetuses in rats.
    Tolyl diiodomethyl sulfone
  • HY-W021008
    Sotolone 28664-35-9
    Sotolone (Dimethylhydroxyfuranone) is an activator of the human olfactory receptor OR8D1. Sotolone activates the human olfactory receptor OR8D1, with EC50 values of 84.98 μM and 167.2 μM for its S-enantiomer and R-enantiomer, respectively. Sotolone has unique aroma profiles: (R)-sotolone exhibits smoky, burnt, herbal and grassy notes; (S)-sotolone presents sweet, milky, sour and nutty notes. Sotolone also acts as an antifungal agent, showing moderate inhibitory activity against Magnaporthe oryzae in vitro.
    Sotolone
Cat. No. 상품명 / Synonyms Application Reactivity