2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-117235R
    Diallyl Trisulfide (Standard) 2050-87-5
    Diallyl Trisulfide (Standard) is the analytical standard of Diallyl Trisulfide. This product is intended for research and analytical applications. Diallyl Trisulfide is an orally active anticancer agent that can be isolated from garlic. Diallyl Trisulfide has the ability to induce apoptosis and exhibits anticancer, anti-inflammatory, antioxidant, and antibacterial activities. Diallyl Trisulfide can be used to study a variety of cancers, including liver, colon and prostate cancer[1][2][3][4].
    Diallyl Trisulfide (Standard)
  • HY-121544A
    Methicillin sodium hydrate 7246-14-2 98%
    Methicillin sodium hydrate is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin sodium hydrate is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins. Methicillin sodium hydrate can be used for the research of skin infections, osteomyelitis, and endocarditis.
    Methicillin sodium hydrate
  • HY-129172A
    PD-1/PD-L1-IN 5 2170209-51-3 98%
    PD-1/PD-L1-IN 5 is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM.
    PD-1/PD-L1-IN 5
  • HY-135327A
    Amphotericin B methyl ester hydrochloride 35375-29-2 98%
    Amphotericin B methyl ester hydrochloride is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B methyl ester hydrochloride is the cholesterol-binding compound possesses significant antifungal activity. Amphotericin B methyl ester hydrochloride disrupts HIV-1 particle production and potently inhibits HIV-1 replication.
    Amphotericin B methyl ester hydrochloride
  • HY-145586A
    Onradivir monohydrate 2375241-19-1 98%
    Onradivir (ZSP1273) monohydrate is an orally active antiviral agent targeting influenza A virus RNA polymerase PB2 subunit with an IC50 of 0.562 nM. Onradivir monohydrate inhibits cap binding to influenza A virus RNA polymerase PB2 subunit, suppresses viral replication, reduces viral titres and RNA loads, and inhibits influenza A virus infection. Onradivir monohydrate maintains high survival rates in influenza A virus-infected mice, and reduces influenza A virus titers in a murine model. Onradivir monohydrate can be used for the research of influenza A virus infection.
    Onradivir monohydrate
  • HY-147217C
    Bepirovirsen sodium scrambled negative control 98%
    Bepirovirsen sodium scrambled negative control is the sequence scrambled negative control of Bepirovirsen sodium.
    Bepirovirsen sodium scrambled negative control
  • HY-147217D
    FAM labled Bepirovirsen sodium 98%
    FAM labled Bepirovirsen sodiumis a FAM labled Bepirovirsen sodium.
    FAM labled Bepirovirsen sodium
  • HY-147217E
    Cy3 labled Bepirovirsen sodium 98%
    Cy3 labled Bepirovirsen sodium is a Cy3 labled Bepirovirsen sodium.
    Cy3 labled Bepirovirsen sodium
  • HY-147358A
    Yimitasvir 1959593-23-7 98%
    Yimitasvir (Emitasvir; DAG-181) is an orally active inhibitor of hepatitis C virus (HCV) nonstructural protein 5A (NS5A). Yimitasvir is applicable to research related to HCV infection.
    Yimitasvir
  • HY-B0975AS
    Penicillin V-d5 1356837-87-0 99.45%
    Penicillin V-d5 (Phenoxymethylpenicillin-d5) is the deuterium labeled Penicillin V. Penicillin V (Phenoxymethylpenicillin) is an orally active antibiotic. Penicillin V inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis.
    Penicillin V-d5
  • HY-W011303R
    Phytosphingosine (Standard) 554-62-1
    Phytosphingosine (Standard) is the analytical standard of Phytosphingosine. This product is intended for research and analytical applications. Phytosphingosine is a phospholipid with anti-inflammatory, antibacterial, and anti-cancer activities, which can induce apoptosis. Phytosphingosine is an immune regulator and can be used in the study of inflammatory skin diseases. Phytosphingosine is also an activator of GPR120 with an IC50 value of 33.4 μM and can be used in the study of type II diabetes[1][2][3][4].
    Phytosphingosine (Standard)
  • HY-P2502
    Hepatitis Virus C NS3 Protease Inhibitor 2 208939-95-1 98%
    Hepatitis Virus C NS3 Protease Inhibitor 2 is a product-based peptide inhibitor of hepatitis C virus (HCV) NS3 protease, with a Ki of 41 nM.
    Hepatitis Virus C NS3 Protease Inhibitor 2
  • HY-P2521
    NS2 (114-121), Influenza 184763-32-4 98%
    NS2 (114-121), Influenza, the 114-121 fragment of influenza nonstructural protein 2 (NS2), is a influenza-derived epitope. NS2 (114-121), Influenza can be used for the research of CD8+ cytotoxic T lymphocyte (CTL) in antiviral immune responses.
    NS2 (114-121), Influenza
  • HY-10046S
    Plerixafor-d4 1246819-87-3 98%
    Plerixafor-d4 is the deuterium labeled Plerixafor. Plerixafor (AMD 3100) is a selective CXCR4 antagonist with an IC50 of 44 nM. Plerixafor, an immunostimulant and a hematopoietic stem cell (HSC) mobilizer, is an allosteric agonist of CXCR7. Plerixafor inhibits HIV-1 and HIV-2 replication with an EC50 of 1-10 nM.
    Plerixafor-d4
  • HY-10237S
    Boceprevir-d9 1256751-11-7 98%
    Boceprevir-d9 is the deuterium labeled Boceprevir. Boceprevir (EBP 520) is a potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with a Ki of 14 nM in both enzyme assay and an EC90 of 350 nM in cell-based replicon assay. Boceprevir inhibits SARS-CoV-2 3CLpro activity.
    Boceprevir-d9
  • HY-10574S
    Rilpivirine-d6 1312424-26-2 98%
    Rilpivirine-d6 is the deuterium labeled Rilpivirine. Rilpivirine (R278474) is a potent and specific diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). Rilpivirine has high antiviral activity against wild-type HIV (EC50=0.4 nM) and mutant viruses (EC50=0.1-2.0 nM). Rilpivirine has a high genetic barrier to resistance development of HIV.
    Rilpivirine-d6
  • HY-17043S
    Loratadine-d4 381727-27-1 98%
    Loratadine-d4 is the deuterium labeled Loratadine. Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators.
    Loratadine-d4
  • HY-17423S
    Abacavir-d4 1260619-56-4 98%
    Abacavir-d4 is the deuterium labeled Abacavir. Abacavir is a potent nucleoside analog reverse-transcriptase inhibitor (NRTI)[1][2].
    Abacavir-d4
  • HY-17426S
    Famciclovir-d4 1020719-42-9 98%
    Famciclovir-d4 is the deuterium labeled Famciclovir. Famciclovir (BRL 42810) is a guanine analogue antiviral agent used for the treatment of various herpesvirus infections.
    Famciclovir-d4
  • HY-17430S
    Amprenavir-d4 1217661-20-5 98%
    Amprenavir-d4 is the deuterium labeled Amprenavir. Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.09 μM.
    Amprenavir-d4
Cat. No. Product Name / Synonyms Application Reactivity