1. Immunology/Inflammation
  2. PD-1/PD-L1
  3. PD-1/PD-L1-IN 5

PD-1/PD-L1-IN 5 

Cat. No.: HY-129172A
Handling Instructions

PD-1/PD-L1-IN 5 is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM.

For research use only. We do not sell to patients.

PD-1/PD-L1-IN 5 Chemical Structure

PD-1/PD-L1-IN 5 Chemical Structure

CAS No. : 2170209-51-3

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Description

PD-1/PD-L1-IN 5 is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM[1].

IC50 & Target

IC50: ≤100 nM (PD-1/PD-L1)[1]

In Vitro

The compounds modulate PD-1/PD-L1 protein/protein interaction and are useful in the treatment of various diseases including infectious diseases and cancer. The compounds can be used as immunomodulators[1].

Molecular Weight

418.47

Formula

C₂₂H₁₈N₄O₃S

CAS No.

2170209-51-3

SMILES

O=C(C(S1)=NC2=C1CNCC2)NC3=CC=CC(C4=CC=C(OCCO5)C5=C4)=C3C#N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

PD-1/PD-L1-IN 5PD-1/PD-L1PD-1/Programmed death-ligand 1Inhibitorinhibitorinhibit

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