PD-1/PD-L1-IN 5
PD-1/PD-L1-IN 5 is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM.
For research use only. We do not sell to patients.
- CAS No.: 2170209-51-3
- Formula: C22H18N4O3S
- Molecular Weight:418.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: ≤100 nM (PD-1/PD-L1)[1]
The compounds modulate PD-1/PD-L1 protein/protein interaction and are useful in the treatment of various diseases including infectious diseases and cancer. The compounds can be used as immunomodulators[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2170209-51-3
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Molecular Weight 418.47
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Formula C22H18N4O3S
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SMILES
O=C(C(S1)=NC2=C1CNCC2)NC3=CC=CC(C4=CC=C(OCCO5)C5=C4)=C3C#N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)