PD-1/PD-L1-IN 5 TFA
PD-1/PD-L1-IN 5 TFA is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM.
For research use only. We do not sell to patients.
- CAS No.: 2170209-52-4
- Formula: C22H18N4O3S.xC2HF3O2
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: ≤100 nM (PD-1/PD-L1)[1]
The compounds modulate PD-1/PD-L1 protein/protein interaction and are useful in the treatment of various diseases including infectious diseases and cancer. The compounds can be used as immunomodulators[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2170209-52-4
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Formula C22H18N4O3S.xC2HF3O2
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SMILES
N#CC1=C(NC(C2=NC3=C(CNCC3)S2)=O)C=CC=C1C4=CC5=C(OCCO5)C=C4.OC(C(F)(F)F)=O.[x]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)