2. Immunology/Inflammation
  3. PD-1/PD-L1
  4. PD-1/PD-L1-IN 5 TFA

PD-1/PD-L1-IN 5 TFA is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM.

For research use only. We do not sell to patients.

PD-1/PD-L1-IN 5 TFA Chemical Structure

PD-1/PD-L1-IN 5 TFA Chemical Structure

CAS No. : 2170209-52-4

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Other Forms of PD-1/PD-L1-IN 5 TFA:

PD-1/PD-L1-IN 5 TFA Related Antibodies

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Description

PD-1/PD-L1-IN 5 TFA is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM[1].

IC50 & Target

IC50: ≤100 nM (PD-1/PD-L1)[1]
In Vitro

The compounds modulate PD-1/PD-L1 protein/protein interaction and are useful in the treatment of various diseases including infectious diseases and cancer. The compounds can be used as immunomodulators[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PD-1/PD-L1-IN 5 TFA Related Antibodies
Formula

C22H18N4O3S.xC2HF3O2
CAS No.
SMILES

N#CC1=C(NC(C2=NC3=C(CNCC3)S2)=O)C=CC=C1C4=CC5=C(OCCO5)C=C4.OC(C(F)(F)F)=O.[x]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PD-1/PD-L1-IN 5 TFA Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PD-1/PD-L1-IN 52170209-52-4PD-1/PD-L1PD-1/Programmed death-ligand 1PD-1PD-L1infectiousdiseasescancerimmunomodulatorInhibitorinhibitorinhibit

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PD-1/PD-L1-IN 5 TFA
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