2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-124162
    Diepoxin σ 152697-41-1 98%
    Diepoxin σ (Sch-49209) is a highly oxygenated antifungal and anticancer natural product. Diepoxin σ can be isolated from the fermentation of N. mangiferae.
    Diepoxin σ
  • HY-124182
    Odalasvir 1415119-52-6 98%
    Odalasvir (ACH-3102) is a potent and selective inhibitor of HCV NS5A, and can be used in research on hepatitis C virus infection.
    Odalasvir
  • HY-124199
    Cephalochromin 25908-26-3 98%
    Cephalochromin is an antibiotic and an inhibitor for bacterial fatty acid synthase (FabI). Cephalochromin inhibits FabI of Staphylococcus aureus and Escherichia coli with IC50 of 1.9 and 1.8 μM. Cephalochromin inhibits gram-positive methicillin-resistant S. aureus (MRSA) and quinolone-resistant S. aureus (QRSA), with MIC of 2-8 µg/mL.
    Cephalochromin
  • HY-124205
    Pepticinnamin E 147317-36-0 98%
    Pepticinnamin E is a Farnesyltransferase (FTase) inhibitor (IC50=42 µM). Pepticinnamin E can be used in cancer and malaria research.
    Pepticinnamin E
  • HY-124210
    Formycin B 13877-76-4 98%
    Formycin B is an antibiotic, which exhibits antiparasitic activity against Leishmania. Formycin B exhibits toxicity to leukocytes, reversibly decreases neutrophils. Formycin B can be used in research about myeloid leukemia.
    Formycin B
  • HY-124250
    9-OxoOTrE 125559-74-2 98%
    9-OxoOTrE (9-KOTrE) is an antifungal agent against B. cinerea, C. herbarum, P. infestans, and P. parasitica, through a mechanism based on their electrophilic nature.
    9-OxoOTrE
  • HY-12429A
    Beclabuvir hydrochloride 958002-36-3 98%
    Beclabuvir (BMS-791325) hydrochloride is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM.
    Beclabuvir hydrochloride
  • HY-124301
    Penicolinate A 1418291-68-5 98%
    Penicolinate A is a picolinic acid derivative. Penicolinate A is isolated from endophytic Penicillium sp. BCC16054. Penicolinate A exhibits antimalarial and antitubercular activities.
    Penicolinate A
  • HY-124305
    ML395 1638957-17-1 98%
    ML395 is a potent and selective allosteric inhibitor of phospholipase D2 with antiviral activity. The cellular PLD1 IC50 value of ML395 exceeds 30,000 nM, while its cellular PLD2 IC50 value is 360 nM. ML395 shows excellent pharmacokinetic characteristics in vitro and physiochemical properties superior to other reported phospholipase inhibitors. ML395 shows interesting antiviral activity in cell-based assays against multiple influenza virus strains (H1, H3, H5, and H7).
    ML395
  • HY-124334
    L-161240 183298-68-2 98%
    L-161240 is an antibiotic, which exhibits antibacterial activity against Escherichia coli, through inhibition of LpxC enzyme (Ki is 50 nM).
    L-161240
  • HY-124360
    NIT 299922-10-4 98%
    NIT is an inhibitor of HIV-1 protease (HIV-1p) with Ki values of 96 and 91 μM for WT HIV-1p and MDR HIV-1p, respectively.
    NIT
  • HY-124364
    RO6889678 1578153-27-1 98%
    RO6889678 is a highly potent HBV capsid formation inhibitor with a complex absorption, distribution, metabolism, and excretion (ADME) profile. RO6889678 is a potent inducer of CYP3A4 and coregulated proteins in human hepatocytes. RO6889678 is metabolized by a combination of CYP3A4-mediated oxidation and UDP-glucuronosyltransferase UGT1A3- and UGT1A1-mediated direct glucuronidation.
    RO6889678
  • HY-124375
    IND81 1426047-52-0 98%
    IND81 is an orally active antiprion with IC50 value of 1.95 μM. IND81 reduces abnormal, misfolded, disease-causing forms of benign prion proteins that are normally present on or within cells.
    IND81
  • HY-124384
    Pseudoanguillosporin A 1159392-22-9 98%
    Pseudoanguillosporin A (Soudanone A) (Compound 3) is an isochromanone that can be isolated from the fungus Cadophora sp.. Pseudoanguillosporin A has significant antifungal activity against Cryptococcus neoformans with a MIC50 of 40 μg/mL. Pseudoanguillosporin A can be used for fungal infection research.
    Pseudoanguillosporin A
  • HY-124408
    Mepronil 55814-41-0 99.91%
    Mepronil, a compound belonging to the carboxyamine group of fungicides, has a particularly strong bactericidal effect on basidiomycete fungi. Mepronil acts as a single point inhibitor of the succinate ubiquinone reductase or succinate dehydrogenase complex. Mepronil can be used in the study of cross resistance and biological infection.
    Mepronil
  • HY-124438
    Herbicidin A 55353-31-6 98%
    Herbicidin A is an adenosine-derived nucleoside antibiotic, but also is a herbicide against dicotyledonous plants. Herbicidin A can be isolated from Streptomyces scopuliridis M40.
    Herbicidin A
  • HY-124439
    Setomimycin 69431-87-4 98%
    Setomimycin is a potent antibiotic. Setomimycin inhibits the SARS-CoV-2 Mpro enzyme with an IC50 value of 12.02 µM. Setomimycin shows anti-inflammatory and antioxidant properties. Setomimycin shows antiproliferative and antitumor activity.
    Setomimycin
  • HY-124456
    Unguinol 36587-59-4 98%
    Unguinol is a depsidone originally isolated from A. unguis. It is an inhibitor of pyruvate phosphate dikinase (PPDK; IC50=42.3 μM). It inhibits the growth of plants utilizing C4, but not C3, carbon fixation. Unguinol also inhibits the growth of the bacteria S. aureus and V. harveyi (GI50s=8.7 and 69.5 μM, respectively) and H460, MCF-7, and SF-268 cancer cells (GI50s=28.2, 50.8, and 44.3 μM, respectively).
    Unguinol
  • HY-124498
    Oxantel 36531-26-7 98%
    Oxantel (CP-14445) is an anthelmintic agent that potently against Trichuris muris. Oxantel inhibits fumarate reductase (Frd) activity in some pathogenic bacteria and inhibits P. gingivalis homotypic biofilm formation (IC50 of 2.2 μM).
    Oxantel
  • HY-124551
    Viridiol 23820-80-6 98%
    Viridiol, a fungal metabolite from Trichodernza viride, shows antifungal activity.
    Viridiol
Cat. No. Product Name / Synonyms Application Reactivity