1. Anti-infection
    Metabolic Enzyme/Protease
  2. HBV
    Cytochrome P450
  3. RO6889678

RO6889678 

Cat. No.: HY-124364
Handling Instructions

RO6889678 is a highly potent HBV capsid formation inhibitor with a complex absorption, distribution, metabolism, and excretion (ADME) profile. RO6889678 is a potent inducer of CYP3A4 and coregulated proteins in human hepatocytes. RO6889678 is metabolized by a combination of CYP3A4-mediated oxidation and UDP-glucuronosyltransferase UGT1A3- and UGT1A1-mediated direct glucuronidation.

For research use only. We do not sell to patients.

RO6889678 Chemical Structure

RO6889678 Chemical Structure

CAS No. : 1578153-27-1

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Description

RO6889678 is a highly potent HBV capsid formation inhibitor with a complex absorption, distribution, metabolism, and excretion (ADME) profile. RO6889678 is a potent inducer of CYP3A4 and coregulated proteins in human hepatocytes. RO6889678 is metabolized by a combination of CYP3A4-mediated oxidation and UDP-glucuronosyltransferase UGT1A3- and UGT1A1-mediated direct glucuronidation[1].

IC50 & Target[1]

CYP3A4

 

Molecular Weight

494.92

Formula

C21H20ClFN4O5S

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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RO6889678
Cat. No.:
HY-124364
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