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Cat. No.: HY-124210

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Formycin B

Formycin B is an antibiotic, which exhibits antiparasitic activity against Leishmania. Formycin B exhibits toxicity to leukocytes, reversibly decreases neutrophils. Formycin B can be used in research about myeloid leukemia.

For research use only. We do not sell to patients.

CAS No.: 13877-76-4
Formula: C₁₀H₁₂N₄O₅
Molecular Weight:268.23

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Formycin B Chemical Structure

CAS No.: 13877-76-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
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Classifications
Bioz

Biological Activity

Description

All Antibiotic Isoforms :

All Parasite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
MDCK	CC₅₀	68 μM Compound: 8	Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by CellTiter96 Aqueous one solution assay Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by CellTiter96 Aqueous one solution assay	[PMID: 35092894]

Chemical Information

CAS No. 13877-76-4
Molecular Weight 268.23
Formula C₁₀H₁₂N₄O₅
SMILES

O[C@H]1[C@@H](O)[C@H](C2=NNC3=C2NC=NC3=O)O[C@@H]1CO
Structure Classification
- Antibiotics
Initial Source
- Microorganisms
Nocardia interforma
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Rainey P, et al., Metabolism and mechanism of action of formycin B in Leishmania. Proc Natl Acad Sci U S A. 1983 Jan;80(1):288-92. [Content Brief]

[2]. Ishizuka M, et al., Biological studies on formycin and formycin B. J Antibiot (Tokyo). 1968 Jan;21(1):5-12. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Formycin B

All Antibiotic Isoforms

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Formycin B Related Classifications

HY-124210 Related Classifications