ML395
Based on 1 publication(s) in Google Scholar
ML395 is a potent and selective allosteric inhibitor of phospholipase D2 with antiviral activity. The cellular PLD1 IC50 value of ML395 exceeds 30,000 nM, while its cellular PLD2 IC50 value is 360 nM. ML395 shows excellent pharmacokinetic characteristics in vitro and physiochemical properties superior to other reported phospholipase inhibitors. ML395 shows interesting antiviral activity in cell-based assays against multiple influenza virus strains (H1, H3, H5, and H7).
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- CAS No.: 1638957-17-1
- Formula: C26H29N5O2
- Molecular Weight:443.54
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Publications Citing Use of MedChemExpress (MCE) ML395
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Biological Activity
Chemical Information
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CAS No. 1638957-17-1
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Molecular Weight 443.54
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Formula C26H29N5O2
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SMILES
O=C(C1=CC=C2C=CC=CC2=C1)NCCN(CC3)CCC3(N(CC4=CC=CN=C4)CN5)C5=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Am J Orthod Dentofacial Orthop
Force threshold-dependent modulation of root resorption via the Nrf2/Keap1/p62 antioxidant pathway during orthodontic tooth movement. [Abstract]2025 Dec 4:S0889-5406(25)00481-0. PMID: 41342829
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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