2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-160681
    OvCHT1-IN-1 1613336-69-8 98%
    OvCHT1-IN-1 (compound 3i) is a potent OvCHT1 inhibitor with IC50 of 0.6 μM .
    OvCHT1-IN-1
  • HY-160791
    Claramine 1430194-56-1 98%
    Claramine is a steroid polyamine with blood-brain barrier permeability. Claramine can regulate the properties of lipid membranes and protect cells from various biological toxins, including misfolded protein oligomers and biological protein-based toxins.
    Claramine
  • HY-160877
    EBOV-IN-2 98%
    EBOV-IN-2 (Compound 2) is an inhibitor of Ebola virus (EBOV) with IC50 values of 0.37 μM and 2.54 μM against Ebola virus glycoprotein pseudotype virus (pEBOV) and African swine fever virus (ASFV), respectively.
    EBOV-IN-2
  • HY-160878
    EBOV-IN-3 2896193-40-9 98%
    EBOV-IN-3 (compound 9) is benzothiazepine compound. EBOV-IN-6 has anti-pEBOV activity with a IC50 value of 0.37 μM.
    EBOV-IN-3
  • HY-160879
    EBOV-IN-4 2896193-43-2 98%
    EBOV-IN-4 (compound 12), a benzothiazepine, is a potent Ebola virus (EBOV) inhibitor with 64.9% inhibitory for EBOV-GP-pseudotype virus (pEBOV) with 10 μM. EBOV-IN-4 is inactive with ASFV.
    EBOV-IN-4
  • HY-160880
    EBOV-IN-5 68207-15-8 98%
    EBOV-IN-5 (compound 14) is an antiviral agent that inhibits Ebola virus (EBOV) infection. EBOV-IN-5 inhibits the binding of the EBOV glycoprotein EBOV-GPcl to NPC1, an indispensable host receptor required for viral fusion/entry.
    EBOV-IN-5
  • HY-160881
    EBOV-IN-6 98%
    EBOV-IN-6 (compound 19) is benzothiazepine compound. EBOV-IN-6 has anti-pEBOV activity with a IC50 value of 10 μM.
    EBOV-IN-6
  • HY-160882
    EBOV-IN-7 68207-16-9 98%
    EBOV-IN-7 (compound 26) is an inhibitor of the Ebola virus EBOV with an IC50 of 2.04 μM against EBOV-GP pseudotyped virus (pEBOV). EBOV-IN-7 has inhibitory effects on cancer cells and inhibits the EBOV-GPcl/NPC1 interaction.
    EBOV-IN-7
  • HY-160883
    EBOV-IN-8 286854-12-4 98%
    EBOV-IN-8 (Compound 30) inhibits Ebola pseudotyped virus (pEBOV) infection with an IC50 of 62.1% at 10 μM.
    EBOV-IN-8
  • HY-160917
    BAY-43-9695 233255-39-5 99.98%
    BAY-43-9695 is a nonnucleosidic with activity against human cytomegalovirus (hCMV) with IC50 of 0.95 and 1.1 μM, using the FACS and PRA methodes. BAY-43-9695 inhibits the HCMV replication with and without presence of serum proteins, with IC50 of 0.53 and 8.42 μM. BAY-43-9695 is the metabolite of Tomeglovir (BAY38-4766) (HY-108261).
    BAY-43-9695
  • HY-160968
    4-Demethoxy-7,9-di-epi-daunorubicin 58957-91-8 98%
    4-Demethoxy-7,9-di-epi-daunorubicin, a derivative of Daunorubicin (HY-13062A), is an anthracycline antibiotics. 4-Demethoxy-7,9-di-epi-daunorubicin can bind to calf thymus DNA and forms a complex with the stacked DNA base pairs. 4-Demethoxy-7,9-di-epi-daunorubicin can inhibit prokaryotic nucleic acid polymerases, including E. coli DNA polymerase I and RNA polymerase. 4-Demethoxy-7,9-di-epi-daunorubicin can be used for researches of cancer and infection.
    4-Demethoxy-7,9-di-epi-daunorubicin
  • HY-160996
    Glucosulfamide 7007-76-3 98%
    Glucosulfamide is a sulfonamide anti-infective compound. Glucosulfamide can be used in solvent preservatives.
    Glucosulfamide
  • HY-161028
    Antibacterial agent 167 1940173-83-0 98%
    Antibacterial agent 167 (compound 13) is an inhibitor of pathogenic bacterial carbonic anhydrases. Antibacterial agent 167 inhibits the growth of N. gonorrhea strains at concentrations ranging from 16 to 64 µg/mL.
    Antibacterial agent 167
  • HY-16102R
    Bismuth subcitrate potassium (Standard) 880149-29-1
    Bismuth subcitrate potassium (Standard) is the analytical standard of Bismuth subcitrate potassium (HY-16102). This product is intended for research and analytical applications. Bismuth subcitrate potassium is a compound bismuth salt with oral activity. Bismuth subcitrate potassium has antibacterial activity and can inhibit the growth of Campylobacter pyloridis with a MIC50 of 8 μg/mL. Bismuth subcitrate potassium can be used in the study of gastrointestinal diseases infected by Campylobacter pyloridis.
    Bismuth subcitrate potassium (Standard)
  • HY-161071
    Antioxidant/anticancer agent 1 1449470-38-5 98%
    Antioxidant/anticancer agent 1 (compound 5) is a pyrimidine-derivatized Schiff base based on pyrimidine hydroxy-1-naphthaldehyde and has antibacterial, antioxidant, antifungal, and anticancer properties. Antioxidant/anticancer agent 1.
    Antioxidant/anticancer agent 1
  • HY-161079
    TDI-8304 2307262-96-8 98%
    TDI-8304, a macrocyclic peptide, is a potent, species selective, and noncovalent Plasmodium falciparum (Pf20S) inhibitor. TDI-8304 shows highly selective for Pf20S over human proteasomes.
    TDI-8304
  • HY-161135
    TBAJ-5307 2332831-92-0 98%
    TBAJ-5307 is a broad spectrum anti-non-tuberculous mycobacteria inhibitor that can target the FO-domain of the engine and preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo.
    TBAJ-5307
  • HY-161148
    FtsZ-IN-9 1273524-44-9 98%
    FtsZ-IN-9 (compound 11) is an antimicrobial agent. FtsZ-IN-9 inhibits the assembly of Mycobacterium smegmatis FtsZ (MsFtsZ)[1].
    FtsZ-IN-9
  • HY-161170
    Antimalarial agent 36 2982633-03-2 98%
    Antimalarial agent 36 (compound 1) is an antimalarial agent, with the EC50s of 58 nM and 42 nM, for Dd2 and 3D7, respectively. Antimalarial agent 36 targets EphA2.
    Antimalarial agent 36
  • HY-161237
    Antitrypanosomal agent 20 98%
    Antitrypanosomal agent 20 (Compd 27) is an anti-trypanosomal, with an IC50 of 0.75 μM for T. b. brucei.
    Antitrypanosomal agent 20
Cat. No. Product Name / Synonyms Application Reactivity