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Cat. No.: HY-161148

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FtsZ-IN-9

FtsZ-IN-9 (compound 11) is an antimicrobial agent. FtsZ-IN-9 inhibits the assembly of Mycobacterium smegmatis FtsZ (MsFtsZ)_[1].

For research use only. We do not sell to patients.

CAS No.: 1273524-44-9
Formula: C₂₆H₂₇NO₄
Molecular Weight:417.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

FtsZ-IN-9 Chemical Structure

CAS No.: 1273524-44-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

FtsZ-IN-9 (compound 11) is an antimicrobial agent. FtsZ-IN-9 inhibits the assembly of Mycobacterium smegmatis FtsZ (MsFtsZ)_[1].

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	CC₅₀	13.5 μM Compound: 11	Cytotoxicity against human CEM-GFP cells after 48 hrs by MTT assay Cytotoxicity against human CEM-GFP cells after 48 hrs by MTT assay	[PMID: 21227704]
CCRF-CEM	EC₅₀	4.2 μM Compound: 11	Antiviral activity against HIV1 NL4.3 infected in human CEM-GFP T cells assessed as inhibition of p24 antigen production after 7 days by ELISA Antiviral activity against HIV1 NL4.3 infected in human CEM-GFP T cells assessed as inhibition of p24 antigen production after 7 days by ELISA	[PMID: 21227704]

Chemical Information

CAS No. 1273524-44-9
Molecular Weight 417.50
Formula C₂₆H₂₇NO₄
SMILES

OC1=C(O)C=CC(/C=C/C(C2=CC=C(NC(C34C[C@H]5C[C@H](C[C@H](C5)C4)C3)=O)C=C2)=O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bhondwe P, et al. An adamantyl-caffeoyl-anilide exhibits broad-spectrum antibacterial activity by inhibiting FtsZ assembly and Z-ring formation. Int J Biol Macromol. 2024 Jan 8;259(Pt 2):129255. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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