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United States

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Cat. No.: HY-161237

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Antitrypanosomal agent 20

Antitrypanosomal agent 20 (Compd 27) is an anti-trypanosomal, with an IC₅₀ of 0.75 μM for T. b. brucei.

For research use only. We do not sell to patients.

Formula: C₂₃H₂₉FN₄O₃
Molecular Weight:428.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Antitrypanosomal agent 20 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Antitrypanosomal agent 20 (Compd 27) is an anti-trypanosomal, with an IC₅₀ of 0.75 μM for T. b. brucei^[1].

IC₅₀ & Target

IC50: 0.75 μM (T. b. brucei)^[1].

All Parasite Isoforms :

Chemical Information

Molecular Weight 428.50
Formula C₂₃H₂₉FN₄O₃
SMILES

O=C(N/C(NCCN1CCOCC1)=N\C2=CC=CC=C2CC)C3=CC(OC)=C(F)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Swapna Varghese, et al. Novel aroyl guanidine anti-trypanosomal compounds that exert opposing effects on parasite energy metabolism. European Journal of Medicinal Chemistry. Available online 17 January 2024, 116162.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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