EBOV-IN-5
EBOV-IN-5 (compound 14) is an antiviral agent that inhibits Ebola virus (EBOV) infection. EBOV-IN-5 inhibits the binding of the EBOV glycoprotein EBOV-GPcl to NPC1, an indispensable host receptor required for viral fusion/entry.
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- No. CAS: 68207-15-8
- Fòrmula: C18H21ClN4O3S
- Peso molecular:408.90
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
Ebola virus[1]
EBOV-IN-5 (compound 14) has a CC50 of 30 μM on HeLa cells and low cytotoxicity on Vero cells with a CC50 >100 μM[1].
EBOV-IN-5 (50 μM) significantly interferes with EBOV - GPcl/NPC1 interaction, IC50 against EBOV-GP-pseudotyped virus (pEBOV) is 4.69 μM[1].
EBOV-IN-5 IC50 against African swine fever virus ASFV is 35.17 μM[1].br /
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 68207-15-8
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Peso molecular 408.90
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Fòrmula C18H21ClN4O3S
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SMILES
O=C(CN(CC)CC)NNC1=C(SC2=CC(Cl)=CC=C2[N+]([O-])=O)C=CC=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EBOV-IN-5 Related Classifications
HY-160880 Related Classifications
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