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EBOV-IN-5 (compound 14) is an antiviral agent that inhibits Ebola virus (EBOV) infection. EBOV-IN-5 inhibits the binding of the EBOV glycoprotein EBOV-GPcl to NPC1, an indispensable host receptor required for viral fusion/entry..

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EBOV-IN-5 Chemical Structure

EBOV-IN-5 Chemical Structure

CAS No. : 68207-15-8

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EBOV-IN-5 Related Antibodies

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Description

EBOV-IN-5 (compound 14) is an antiviral agent that inhibits Ebola virus (EBOV) infection. EBOV-IN-5 inhibits the binding of the EBOV glycoprotein EBOV-GPcl to NPC1, an indispensable host receptor required for viral fusion/entry.[7][1].

IC50 & Target

Ebola virus[1]
In Vitro

EBOV-IN-5 (compound 14) has a CC50 of 30 μM on HeLa cells and low cytotoxicity on Vero cells with a CC50 >100 μM[1].
EBOV-IN-5 (50 μM) significantly interferes with EBOV - GPcl/NPC1 interaction, IC50 against EBOV-GP-pseudotyped virus (pEBOV) is 4.69 μM[1].
EBOV-IN-5 IC50 against African swine fever virus ASFV is 35.17 μM[1].br /

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

EBOV-IN-5 Related Antibodies
Molecular Weight

408.90

Formula

C18H21ClN4O3S
CAS No.
Unlabeled Cas

SMILES

O=C(CN(CC)CC)NNC1=C(SC2=CC(Cl)=CC=C2[N+]([O-])=O)C=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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EBOV-IN-5 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EBOV-IN-568207-15-8OthersInhibitorinhibitorinhibit

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