2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N12249
    7-Deoxy-trans-dihydronarciclasine 145987-74-2 98%
    7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC50: 1.80 μM). 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the Aβ and APP levels in the cerebral cortex of Tg2576 mice.
    7-Deoxy-trans-dihydronarciclasine
  • HY-N12258
    Aranciamycin A 960622-70-2 98%
    Aranciamycin A is an anthracyclic antibiotic and can be isolated from Streptomyces. Aranciamycin A shows antibacterial activity against M. bovis and B. subtilis with the MIC values of 30 and 7.5 µM, respectively.
    Aranciamycin A
  • HY-N12260
    Benanomicin A 116249-65-1 98%
    Benanomicin A is a microbial metabolite and can be isolated from Actinomycetes.Benanomicin has antifungal activitya and inhibits HIV-1 viral infection in MT-4 cells.
    Benanomicin A
  • HY-N12264
    Burnettramic acid A 2334483-46-2 98%
    Burnettramic acid A is an antibiotic, which can be isolated from Aspergillus burnettii. Burnettramic acid A exhibits antibacterial and antifungal activities, with IC50 of 0.2, 0.5, 2.3 and 5.9 μg/mL, for Saccharomyces cerevisiae, Candida albicans, Bacillus subtilis and Staphylococcus aureus, respectively. Burnettramic acid A exhibits cytotoxicity in cancer cell NS-1 with IC50 of 13.8 μg/mL.
    Burnettramic acid A
  • HY-N12276
    (±)-Emodin bianthrone 61281-20-7 98%
    (±)-Emodin bianthrone (compound 10), a natural product, exhibits antimalarial, antitubercular and ntifungal activities.
    (±)-Emodin bianthrone
  • HY-N12320
    Majoranaquinone 1596355-59-7 98%
    Majoranaquinone exhibits a high antibacterial effect against 4 Staphylococcus, 1 Moraxella, and 1 Enterococcus strains. Majoranaquinone shows substantial efflux pump inhibitory activity in Escherichia coliATCC 25922 strain. Majoranaquinone is found to be an effective biofilm formation inhibitor on E.coli, ATCC 25922 and E. coli K-12 AG100 bacteria.
    Majoranaquinone
  • HY-N12325
    3,4-Dihydroxyallylbenzene 3,4-di-O-glucoside 454473-97-3 98%
    3,4-Dihydroxyallylbenzene 3,4-di-O-glucoside (Compound 4) is a phenylpropanoid glycoside. 3,4-Dihydroxyallylbenzene 3,4-di-O-glucoside is found in the the dragon’s blood of Dracaena cambodiana. 3,4-Dihydroxyallylbenzene 3,4-di-O-glucoside exhibits antibacterial activity.
    3,4-Dihydroxyallylbenzene 3,4-di-O-glucoside
  • HY-N12362
    Antiviral agent 41 68622-73-1 98%
    Antiviral agent 41 (compound 5) is a diarylheptanoid isolated from Alpinia officinarum. Antiviral agent 41 exhibits potential antiviral activity against influenza virus in vitro.
    Antiviral agent 41
  • HY-N12389
    Quellenin 2243042-31-9 98%
    Quellenin is an anti-saprolegnia compound. Quellenin can be isolated from deep-sea fungus Aspergillus sp. YK-76
    Quellenin
  • HY-N12407
    Peridinin 33281-81-1 98%
    Peridinin is a hydroxylated carotenoid ketone that exhibits inhibitory activity against DENV NS2B/NS3 protease and all dengue virus serotypes (DENV-1, DENV-2, DENV-3, DENV-4). Peridinin inhibits dengue virus production and reduces viral titers. Peridinin is applicable to research related to dengue virus infection.
    Peridinin
  • HY-N12421
    Paulomycin A 81988-77-4 98%
    Paulomycin A (Volonomycin A) has anti-Gram-positive bacteria effect, and it has inhibitory effect on Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin and Macrolide antibiotics.
    Paulomycin A
  • HY-N12452
    Myrrhterpenoid O 2604667-43-6 98%
    Myrrhterpenoid O (Compound 18) is a sesquiterpenoid compound that exhibits good inhibitory activity against Plasmodium falciparum (IC50 = 21 μM).
    Myrrhterpenoid O
  • HY-N12461
    Cucurbitacin F 5939-57-1 98%
    Cucurbitacin F is a tetracyclic protostane-type triterpenoid with low toxicity, antibacterial and anti-inflammatory activities, and is also a related compound of Cucurbitacin B (HY-N0416). Cucurbitacin F widely exists in plants such as Cucurbitaceae plants, Quisqualis indica and Sorbaria sorbifolia. Cucurbitacin F acts as an actin aggregator and reduces cell viability in a dose-dependent manner. Cucurbitacin F induces apoptosis by triggering G2/M phase cell cycle arrest and activating the caspase-3-dependent apoptosis.
    Cucurbitacin F
  • HY-N12524
    Cyclo(prolyltyrosyl) 5654-84-2 98%
    Cyclo(prolyltyrosyl) is a natural compound that can be found in various microorganisms and marine sponges. Cyclo(prolyltyrosyl) has antibacterial, phytotoxic and cytotoxic properties.
    Cyclo(prolyltyrosyl)
  • HY-N12538
    trans-Cinnamic anhydride 21947-71-7 98%
    trans-Cinnamic anhydride is a Parasite inhibitor tnat can be isolated from Cinnamomum zeylanicum and exhibits moderate activity against Plasmodium falciparum.
    trans-Cinnamic anhydride
  • HY-N12552
    Cucurbitacin IIa 2-O-β-D-glucoside 77704-34-8 98%
    Cucurbitacin IIa 2-O-β-D-glucoside is a glycoside cucurbitacin isolated from the genus Hemsleya (Cucurbitaceae). Extracts of Hemsleya have the potential to be used in research on bronchitis, bacillary dysentery, and tuberculosis.
    Cucurbitacin IIa 2-O-β-D-glucoside
  • HY-N12553
    4-Ethyloctane 15869-86-0
    4-Ethyloctane is an active ingredient that can be extracted from peony. 4-Ethyloctane has strong antibacterial activity against Staphylococcus aureus (MIC = 0.04 mg/mL). 4-Ethyloctane can be used for research on bacterial infections.
    4-Ethyloctane
  • HY-N12591
    Iso-isariin B 2326436-93-3 98%
    Iso-isariin B is an analogue of cyclocarboxyphenate, which can be used in antifungal studies.
    Iso-isariin B
  • HY-N12600
    Thiolopyrrolone A 3034042-33-3 98%
    Thiolopyrrolone A (compound 1) exhibits antibacterial activities against BCG, M. tuberculosis and S. aureus with minimum inhibitory concentrations (MIC) of 10, 10 and 100 μg/mL, respectively.
    Thiolopyrrolone A
  • HY-N12606
    Neodidymelliosides A 98%
    Neodidymelliosides A (compound 1)It is a secondary metabolite of fungi and has a significant inhibitory effect on Staphylococcus aureus and Candida albicans biofilms. Neodidymelliosides AIt also has anti-cancer activity and can inhibit KB3.1 (cervix),PC-3 (prostate),MCF-7(breast),SKOV-3 (ovary),A431 (skin )and A549 (lung )Cell viability of cell lines.
    Neodidymelliosides A
Cat. No. Product Name / Synonyms Application Reactivity