Neodidymelliosides A
Neodidymelliosides A (compound 1)It is a secondary metabolite of fungi and has a significant inhibitory effect on Staphylococcus aureus and Candida albicans biofilms. Neodidymelliosides AIt also has anti-cancer activity and can inhibit KB3.1 (cervix),PC-3 (prostate),MCF-7(breast),SKOV-3 (ovary),A431 (skin )and A549 (lung )Cell viability of cell lines.
For research use only. We do not sell to patients.
- Formula: C51H96O13
- Molecular Weight:917.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A-431 | IC50 |
4.8 μM
Compound: 1
|
Antiproliferative activity against human A-431 cells assessed as reduction in cell growth incubated for 5 days by MTT assay
Antiproliferative activity against human A-431 cells assessed as reduction in cell growth incubated for 5 days by MTT assay
|
[PMID: 38351796] |
| A549 | IC50 |
4.8 μM
Compound: 1
|
Antiproliferative activity against human A549 cells assessed as reduction in cell growth incubated for 5 days by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell growth incubated for 5 days by MTT assay
|
[PMID: 38351796] |
| KB 3-1 | IC50 |
8.3 μM
Compound: 1
|
Antiproliferative activity against human KB-3-1 cells assessed as reduction in cell growth incubated for 5 days by MTT assay
Antiproliferative activity against human KB-3-1 cells assessed as reduction in cell growth incubated for 5 days by MTT assay
|
[PMID: 38351796] |
| L929 | IC50 |
8.1 μM
Compound: 1
|
Cytotoxicity against mouse L929 cells assessed as reduction in cell viability incubated for 5 days by MTT assay
Cytotoxicity against mouse L929 cells assessed as reduction in cell viability incubated for 5 days by MTT assay
|
[PMID: 38351796] |
| MCF7 | IC50 |
4.8 μM
Compound: 1
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 5 days by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 5 days by MTT assay
|
[PMID: 38351796] |
| PC-3 | IC50 |
4.8 μM
Compound: 1
|
Antiproliferative activity against human PC-3 cells assessed as reduction in cell growth incubated for 5 days by MTT assay
Antiproliferative activity against human PC-3 cells assessed as reduction in cell growth incubated for 5 days by MTT assay
|
[PMID: 38351796] |
| SK-OV-3 | IC50 |
4.8 μM
Compound: 1
|
Antiproliferative activity against human SK-OV-3 cells assessed as reduction in cell growth incubated for 5 days by MTT assay
Antiproliferative activity against human SK-OV-3 cells assessed as reduction in cell growth incubated for 5 days by MTT assay
|
[PMID: 38351796] |
Chemical Information
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Molecular Weight 917.30
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Formula C51H96O13
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SMILES
C/C(CCCC(O)(C)CCCC(O)(CCCC(O)(CCCC(O)(CCCC(O)(CCC(C(O)(C)C)O)C)C)C)C)=C\CC/C(C)=C/CC/C(C)=C/CO[C@H]1[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)O
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Structure Classification
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Initial Source
Neodidymelliopsis negundinis
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)