2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N2026S
    Propylparaben-d7 1246820-92-7 98%
    Propylparaben-d7 (Propyl parahydroxybenzoate-d7) is the deuterium labeled Propylparaben (HY-N2026). Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is an orally active weak estrogen receptor agonist. Propylparaben regulates the PI3K-AKT and JNK signaling pathways, and induces oxidative stress. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods, and can be used in studies related to ovarian aging and myocardial ischemia-reperfusion injury.
    Propylparaben-d7
  • HY-N2048R
    2,2':5',2''-Terthiophene (Standard) 1081-34-1 98%
    2,2':5',2''-Terthiophene (Standard) is the analytical standard of 2,2':5',2''-Terthiophene. This product is intended for research and analytical applications. 2,2':5',2''-Terthiophene (α-Terthiophene) is an oligomer of the heterocycle thiophene. 2,2':5',2''-Terthiophene has been employed as building block for the organic semi-conductor polythiophene.
    2,2':5',2''-Terthiophene (Standard)
  • HY-N20617
    (2E,6E,10E)-12-Hydroxyfarnesol 69809-46-7 98%
    (2E,6E,10E)-12-Hydroxyfarnesol is a metabolite of Farnesol (HY-Y0248A). (2E,6E,10E)-12-Hydroxyfarnesol forms via CYP2E1- and CYP2C19-mediated ω-hydroxylation of Farnesol in mammalian systems, and via CYP2E1-catalyzed selective hydroxylation of Farnesol in mammalian cells. (2E,6E,10E)-12-Hydroxyfarnesol is produced by the endophytic fungus Aspergillus sp. AST0006. When cholesterol synthesis is blocked, (2E,6E,10E)-12-Hydroxyfarnesol acts as a precursor for the formation of α,β-dicarboxylic acid.
    (2E,6E,10E)-12-Hydroxyfarnesol
  • HY-N20618
    Spicifernin 129514-40-5
    Spicifernin is a plant growth regulator produced by the fermentation of Cochliobolus sativus. Spicifernin promotes the elongation of roots, stems and the second leaf sheath of rice seedlings at low concentrations; while it inhibits the elongation of roots and stems of rice seedlings at high concentrations.
    Spicifernin
  • HY-N20619
    Sterekunthal B 475673-78-0
    Sterekunthal B is a naphthoquinone compound and antimalarial agent. Sterekunthal B can be isolated from plants of the Bignoniaceae family, including the root bark of Stereospermum colais. Sterekunthal B inhibits the growth of Chloroquine (HY-17589A)-sensitive Plasmodium falciparum strain PoW with an IC50 of 23.3 μg/mL. Sterekunthal B also inhibits the growth of Chloroquine-resistant Plasmodium falciparum strain Dd2 with an IC50 of 15.2 μg/mL. Sterekunthal B exhibits non-selective cytotoxicity toward endothelial cells. Sterekunthal B can be used in malaria-related research.
    Sterekunthal B
  • HY-N20632
    Maltol-3-O-(4'-O-p-coumaroyl-6'-O-(3-hydroxy-3-methylglutaroyl))-β-glucopyranoside 942503-47-1 98%
    Maltol-3-O-(4'-O-p-coumaroyl-6'-O-(3-hydroxy-3-methylglutaroyl))-β-glucopyranoside is a sortase A inhibitor of Streptococcus mutans, with an IC50 value of 94.3 μM. Maltol-3-O-(4'-O-p-coumaroyl-6'-O-(3-hydroxy-3-methylglutaroyl))-β-glucopyranoside inhibits saliva-induced aggregation of Streptococcus mutans. Maltol-3-O-(4'-O-p-coumaroyl-6'-O-(3-hydroxy-3-methylglutaroyl))-β-glucopyranoside can be used in caries-related research.
    Maltol-3-O-(4'-O-p-coumaroyl-6'-O-(3-hydroxy-3-methylglutaroyl))-β-glucopyranoside
  • HY-N20641
    Turonicin A 3059457-35-8
    Turonicin A is an anti-fungal and anti-bacterial agent found in Australian Streptomyces sp. MST-123921. Turonicin A inhibits growth of Candida albicans and Saccharomyces cerevisiae fungi. Turonicin A inhibits growth of Bacillus subtilis and Staphylococcus aureus bacteria. Turonicin A can be used for the research of fungal infections, bacterial infections.
    Turonicin A
  • HY-N20645
    Capricostatin A
    Capricostatin A is a glycosylated heteromeric depsipeptide and Antibacterial agent. Capricostatin A is present in the fungus Austroacremonium gemini MST-FP2131. Capricostatin A inhibits the growth of Gram-positive bacteria, including Bacillus subtilis, Staphylococcus aureus, and MRSA. Capricostatin A exhibits no antifungal activity against Saccharomyces cerevisiae and no cytotoxicity against mammalian cells. Capricostatin A can be used in the research of bacterial infections caused by Bacillus subtilis and Staphylococcus aureus.
    Capricostatin A
  • HY-N2071R
    Cedrol (Standard) 77-53-2 98%
    Cedrol (Standard) is the analytical standard of Cedrol. This product is intended for research and analytical applications. Cedrol is a potent competitive inhibitor of cytochrome P-450(CYP) enzyme. Cedrol plays an anticancer role by inducing cell cycle arrest and Caspase-dependent apoptosis. Cedrol acts as a neutrophil agonist that can desensitize cells to subsequent stimulation of N-formyl peptides. Cedrol prevents neuropathic pain caused by chronic contractile injury by inhibiting oxidative stress and inflammation. In addition, Cedrol has antibacterial, hair loss prevention and anti-anxiety properties.
    Cedrol (Standard)
  • HY-N2116R
    Ginkgolic acid C17:1 (Standard) 111047-30-4
    Ginkgolic acid C17:1 (Standard) is the analytical standard of Ginkgolic acid C17:1. This product is intended for research and analytical applications. Ginkgolic acid C17:1 is a fatty acid synthase (FAS) inhibitor with an IC50 of 10.5 µM. Ginkgolic acid C17:1 shows anti-tumor activity by inhibiting the phosphorylation of STAT3 and inducing apoptosis. Ginkgolic acid C17:1 can block the interaction between S-RBD and ACE2, and has anti-SARS-CoV-2-S pseudovirus activity. Ginkgolic acid C17:1 inhibits the biofilm formation of enterohemorrhagic Escherichia coli and Staphylococcus aureus.
    Ginkgolic acid C17:1 (Standard)
  • HY-N2208A
    Isobavachromene 52801-22-6 98.45%
    Isobavachromene is an antibacterial agent.
    Isobavachromene
  • HY-N2211R
    Picfeltarraenin IB (Standard) 97230-46-1
    Picfeltarraenin IB (Standard) is the analytical standard of Picfeltarraenin IB. This product is intended for research and analytical applications. Picfeltarraenin IB, a triterpenoid obtained from Picriafel-terrae Lour (P.fel-terrae), is an acetylcholinesterase (AChE) inhibitor. Picfeltarraenin IB can be used for the treatment of herpes infections, cancer and inflammation.
    Picfeltarraenin IB (Standard)
  • HY-N2229R
    Rhapontigenin (Standard) 500-65-2
    Rhapontigenin (Standard) is the analytical standard of Rhapontigenin. This product is intended for research and analytical applications. Rhapontigenin is a natural analog of resveratrol with anticancer, antioxidant, antifungal and antibacterial activities. Rhapontigenin is amechanism-based, potent and selective cytochrome P450 1A1 inactivator (IC50 = 400 nM). Rhapontigenin exhibits 400-fold and 23-fold selectivity for P450 1A1 over P450 1A2 and P450 1B1, respectively.
    Rhapontigenin (Standard)
  • HY-N2230R
    N-p-trans-Coumaroyltyramine (Standard) 36417-86-4
    N-p-trans-Coumaroyltyramine (Standard) is the analytical standard of N-p-trans-Coumaroyltyramine (HY-N2230). This product is intended for research and analytical applications. N-p-trans-Coumaroyltyramine is a natural phenolic amide compound and an inhibitor of AChE (IC50: 122 μM) and α-glucosidase (IC50: 2.7 μM). N-p-trans-Coumaroyltyramine also has anti-trypanosomal activity, with an IC50 of 13.3 µM against T. brucei rhodesiense. N-p-trans-Coumaroyltyramine can be used in the research of diseases such as Alzheimer's disease.
    N-p-trans-Coumaroyltyramine (Standard)
  • HY-N2340A
    D-(+)-Melezitose hydrate 207511-10-2 98.0%
    D-(+)-Melezitose hydrate ((+)-Melezitose hydrate) can be used to identify clinical isolates of indole-positive and indole-negative Klebsiella spp.
    D-(+)-Melezitose hydrate
  • HY-N2343R
    Procyanidin A2 (Standard) 41743-41-3
    Procyanidin A2 (Standard) is the analytical standard of Procyanidin A2. This product is intended for research and analytical applications. Procyanidin A2 is a flavonoid found in grapes, with anti-cancer, antioxidant, antimicrobial and anti-inflammation activity.
    Procyanidin A2 (Standard)
  • HY-N2369R
    Chelidonine (Standard) 476-32-4
    Chelidonine (Standard) is the analytical standard of Chelidonine. This product is intended for research and analytical applications. Chelidonine, an isoquinoline alkaloid, can be isolated from Chelidonium majus L.. Chelidonine causes G2/M arrest and induces caspase-dependent and caspase-independent apoptosis, and prevents cell cycle progression of stem cells in Dugesia japonica. Chelidonine has cytotoxic activity against melanoma cell lines. with anticancer and antiviral activity.
    Chelidonine (Standard)
  • HY-N2381R
    Menthone (Standard) 10458-14-7 98%
    Menthone (Standard) is the analytical standard of Menthone. This product is intended for research and analytical applications. Menthone, an orally active monoterpene that can be isolated from plants and Mentha oil with antibacterial, antitumor, antioxidation, and antivirus properties. Menthone is a main volatile component of the essential oil, and has anti-Inflammatory properties in Schistosoma mansoni infection and rheumatoid arthritis.
    Menthone (Standard)
  • HY-N2387R
    Pinosylvin (Standard) 22139-77-1 98%
    Pinosylvin (Standard) is the analytical standard of Pinosylvin. This product is intended for research and analytical applications. Pinosylvin is a pre-infectious stilbenoid toxin isolated from the heartwood of Pinus species, has anti-bacterial activities. Pinosylvin is a resveratrol analogue, can induce cell apoptosis and autophapy in leukemia cells.
    Pinosylvin (Standard)
  • HY-N2392S
    Kukoamine A-d8 dihydrochloride 98%
    Kukoamine A-d8 (dihydrochloride) is deuterium labeled Kukoamine A. Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor of trypanothione reductase (Ki, 1.8 μM), with antihypertensive activity.
    Kukoamine A-d8 dihydrochloride
Cat. No. Product Name / Synonyms Application Reactivity