Turonicin A
Turonicin A is an anti-fungal and anti-bacterial agent found in Australian Streptomyces sp. MST-123921. Turonicin A inhibits growth of Candida albicans and Saccharomyces cerevisiae fungi. Turonicin A inhibits growth of Bacillus subtilis and Staphylococcus aureus bacteria. Turonicin A can be used for the research of fungal infections, bacterial infections.
For research use only. We do not sell to patients.
- CAS No.: 3059457-35-8
- Formula: C63H99N3O15
- Molecular Weight:1138.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NFF | IC50 |
80 μM
Compound: 1
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Cytotoxicity against human NFF cells assessed as inhibition of cell growth measured after 48 hrs by resazurin staining based analysis
Cytotoxicity against human NFF cells assessed as inhibition of cell growth measured after 48 hrs by resazurin staining based analysis
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[PMID: 37526586] |
In Vitro
Turonicin A (48 h) exhibits moderate antibacterial activity against Bacillus subtilis (MIC 0.097 μg/mL, 85 nM) and Staphylococcus aureus (MIC 0.39 μg/mL, 340 nM)[1].
Turonicin A (48 h) exhibits very potent antifungal activity against Candida albicans (MIC 0.0031 μg/mL, 2.7 nM) and Saccharomyces cerevisiae (MIC 0.0008 μg/mL, 0.7 nM)[1].
Turonicin A (96 h) exhibits low cytotoxicity against NS-1 murine myeloma cells (IC50 44 μM) and no cytotoxicity against NFF neonatal foreskin fibroblasts up to >80 μM[1].
Turonicin A (72 h) shows no herbicidal activity against Eragrostis tef seed germination up to >100 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Parmacokinetics
Chemical Information
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CAS No. 3059457-35-8
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Molecular Weight 1138.47
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Formula C63H99N3O15
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SMILES
OC(/C(C)=C/C=C/C=C/C=C/CC/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@H](O)/C=C/C=C/C=C/C=C/C=C/C[C@H](O)[C@H](C)C(C[C@@H](C[C@H](O)C[C@H](O)/C=C/C[C@@H](O)C[C@H](O)C[C@@H](O)C[C@H](O)/C=C/C[C@H](O)/C=C/C[C@H](O)CCCNC(N)=N)O)=O)=O
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Structure Classification
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Initial Source
Streptomyces sp.
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Turonicin A Related Classifications
HY-N20641 Related Classifications
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