2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W012475
    cis-3-Hexenyl benzoate 25152-85-6 98%
    cis-3-Hexenyl benzoate is a volatile organic compound with a grassy aroma, widely used in the fragrance and cosmetic industries. It exhibits weak antifungal activity. cis-3-Hexenyl benzoate shows no significant risks in genotoxicity, reproductive toxicity, or environmental toxicity, and its skin sensitization potential is controllable within defined concentration limits.
    cis-3-Hexenyl benzoate
  • HY-W013767
    Thiodicarb 59669-26-0 98%
    Thiodicarb is a carbamate insecticide used to control flies in animal and poultry houses and dairies. Thiodicarb is metabolized into methomyl in animals and plants, and subsequently degraded into carbon dioxide and acetonitrile.
    Thiodicarb
  • HY-W016584
    4,5-Dichlorocatechol 3428-24-8 98%
    4,5-Dichlorocatechol is a substrate of the broad-spectrum chlorocatechol 1,2-dioxygenase of pseudomonas chlororaphis RW71. The Ki values for 4,5-dichlorocatechol is 30 nM for the dioxygenase of the Chlorobenzoate-degrading strain Pseudomonas putida AC27 and 4 nM for the dioxygenase of Acidovorax sp. strain PS14.
    4,5-Dichlorocatechol
  • HY-W016937
    Moroxydine 3731-59-7 98%
    Moroxydine (ABOB) is a broad-spectrum agent with multi-antiviral activities against DNA and RNA viruses, including influenza virus, herpes simplex, varicella zoster, measles, mumps disease, hepatitis C virus, etc. Moroxydine exhibits excellent antiviral activity and shows low cytotoxicity to cells infected by dsRNA viruses (grass carp reovirus, GCRV) and large DNA viruses (giant salamander iridovirus, GSIV). Moroxydine blocks the GCRV-induced cytopathic effects and eliminates nucleocapsids in ctenopharyngodon idella kidney (CIK) cells to keep the normal morphological structure. Moroxydine significantly inhibits the apoptosis, the caspase 3 activity, Bax expression and down-regulates Bcl-2 levels[1][2][3].
    Moroxydine
  • HY-W017143
    Antifungal agent 158 27593-23-3 98%
    Antifungal agent 158 is an α-pyrone derivative that can be found in Trichoderma harzianum, exhibiting antifungal activity against select plant-pathogenic fungi, including Chaetomium spp., Curvularia lunata, and Aspergillus flavus. Antifungal agent 158 is non-toxic to greenhouse-grown bean, corn, and tobacco plants. Antifungal agent 158 can be used for research on Aspergillus flavus infection.
    Antifungal agent 158
  • HY-W023253
    Biclotymol 15686-33-6 98%
    Biclotymol is an antimicrobial agent against gram-positive cocci. Biclotymol inhibits Streptococcus pneumoniae and Haemophilus influenzae, with MIC of 150 and 150 μM. Biclotymol exhibits anti-inflammatory and analgesic activity and ameliorates the otolaryngology infection and throat sore.
    Biclotymol
  • HY-W024297
    VP-4509 2190144-51-3 98%
    VP-4509, an anti-methicillin‐resistant Staphylococcus aureus (MRSA) agent, with the MIC of 49.3 µM. VP-4509 also possesses high antibacterial activity towards gram-negative bacteria P. aeruginosa.
    VP-4509
  • HY-W026467
    MMV665916 896356-25-5 98%
    MMV665916, a quinazolinedione derivative, is an antimalarial agent. MMV665916 displays antiplasmodial activity against P. falciparum FcB1 strain with EC50 value of 0.4 μM and presents the high selectivity index (SI>250).
    MMV665916
  • HY-W026644
    Acridine-9-carboxaldehyde 885-23-4 98.0%
    Acridine-9-carboxaldehyde (Acridine-9-carbaldehyde) is a bioactive compound with potential antibacterial and antitumor activities. Acridine-9-carboxaldehyde is widely used as a building block in compound development to synthesize various bioactive derivatives. Acridine-9-carboxaldehyde exhibits significant cytotoxicity against certain cancer cells, making it an important candidate in cancer inhibition research.
    Acridine-9-carboxaldehyde
  • HY-W027631
    cis-2-Butene-1,4-diol 6117-80-2
    cis-2-Butene-1,4-diol, an industrial product, can be used for the synthesis of antiviral product oxetanocin A. cis-2-Butene-1,4-diol is a probe for studying isomerization versus hydrogenation and hydrogenolysis reactions.
    cis-2-Butene-1,4-diol
  • HY-W037817
    Dimethyl L-glutamate 6525-53-7 98%
    Dimethyl L-glutamate (Dimethyl glutamate), a membrane-permeable analog of Glutamate, can stimulate insulin release induced by Glucose. Dimethyl L-glutamate suppresses the KATP channel activities. Dimethyl L-glutamate inhibits E. gracilis growth and causes abnormal cell division. Dimethyl L-glutamate can be used in the research of diabetes, glucose transport, phosphorylation, and further metabolism.
    Dimethyl L-glutamate
  • HY-W040028
    Cartap hydrochloride 15263-52-2 98%
    Cartap hydrochloride, an organonitrogen insecticide, can cause a marked irreversible Ca2+-dependent contracture in both isolated mouse and rabbit phrenic nerve-diaphragms. Cartap hydrochloride significantly increases the level of endogenous reactive oxygen species (ROS) in C2C12 cells.
    Cartap hydrochloride
  • HY-W040171
    Tefluthrin 79538-32-2 98%
    Tefluthrin is a pyrethroid insecticide. Tefluthrin prolongs the opening time of Nav1.6 sodium channels, leading to membrane depolarization and conductance block in the insect nervous system, thereby disrupting neural function.
    Tefluthrin
  • HY-W040298
    Ciprofloxacin lactate 97867-33-9 98%
    Ciprofloxacin (Bay-09867) lactate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin lactate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin lactate has anti-proliferative activity and induces apoptosis. Ciprofloxacin lactate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
    Ciprofloxacin lactate
  • HY-W048303
    L-Azatyrosine 58525-82-9 98%
    L-Azatyrosine is an antitumor antibiotic isolated from Streptomyces chibaensis. L-Azatyrosine can restore normal phenotypic behavior to transformed cells bearing oncogenic Ras genes.
    L-Azatyrosine
  • HY-W054427
    Ro 13-3978 70842-04-5 98%
    Ro 13-3978 is an orally active antischistosomal agent. Ro 13-3978 exhibits excellent in vivo antischistosomal activity against juvenile and adult Schistosoma mansoni infections. Ro 13-3978 shows no in vivo activity against E. caproni and F. hepatica. Ro 13-3978 blocks dihydrotestosterone-induced proliferation of androgen-dependent cells. Ro 13-3978 can be used in research related to schistosomiasis.
    Ro 13-3978
  • HY-W064918
    NITD-304 1473450-60-0 98%
    NITD-304 is an orally active anti-tuberculosis agent. NITD-304 exerts inhibitory and bactericidal activities gainst Mycobacterium tuberculosis and multidrug-resistant Mycobacterium tuberculosis. NITD-304 inhibits mycobacterial cell wall biosynthesis and demonstrates synergistic or additive growth inhibitory activity with select antibacterial agents. NITD-304 shows low risk of cardiotoxicity and drug-drug interactions, with no inhibition of major cytochrome P-450 enzymes or hERG channel. NITD-304 can be used for the research of tuberculosis and multidrug-resistant tuberculosis.
    NITD-304
  • HY-W065835
    2-Bromoaldisine 96562-96-8
    2-Bromoaldisine is a pyrrole alkaloid that can be isolated from the Red Sea: marine sponge Stylissa carter. 2-Bromoaldisine inhibits HIV-1 vector infection. 2-Bromoaldisine inhibits Raf/MEK/MAPK pathway.
    2-Bromoaldisine
  • HY-W083373
    (E)-3,4-Dimethoxychalcone 53744-27-7 98%
    (E)-3,4-Dimethoxychalcone is an isoform of 3,4-Dimethoxychalcone (HY-W083373A), a potential antimicrobial and antioxidant agent.
    (E)-3,4-Dimethoxychalcone
  • HY-W083821
    1-[(4-Nitrophenyl)methyl]-1,4-diazepane 118158-53-5 98%
    1-[(4-Nitrophenyl) methyl]-1,4-diazepane (1-(4-Nitrobenzyl)-1,4-diazepane) is an anti-biofilm agent. 1-[(4-Nitrophenyl) methyl]-1,4-diazepane reduces biofilm formation in Escherichia coli. 1-[(4-Nitrophenyl) methyl]-1,4-diazepane is used for the research of Escherichia coli biofilm-related infections.
    1-[(4-Nitrophenyl)methyl]-1,4-diazepane
Cat. No. Product Name / Synonyms Application Reactivity