L-Azatyrosine
L-Azatyrosine is an antitumor Antibiotic. L-Azatyrosine is present in Streptomyces chibanensis. L-Azatyrosine inhibits the growth of K-ras-transformed cells without affecting wild-type cells. L-Azatyrosine exhibits anticancer activity against prostate cancer. L-Azatyrosine can be used in studies related to prostate cancer.
For research use only. We do not sell to patients.
- CAS No.: 58525-82-9
- Formula: C8H10N2O3
- Molecular Weight:182.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Microbial Metabolite |
K-RAS |
L-Azatyrosine inhibits the growth of NIH3T3 cells transformed by the K-ras oncogene, while exerting almost no effect on wild-type cells[2].
L-Azatyrosine induces Ras-mediated differentiation of PC12 cells and potently inhibits the tumorigenic growth of androgen-independent prostate cancer cell lines including TSU-Prl, DU-145 and PC-3, restoring them to a non-tumorigenic phenotype[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 58525-82-9
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Molecular Weight 182.18
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Formula C8H10N2O3
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SMILES
OC([C@@H](N)CC1=CC=C(O)C=N1)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
L-Azatyrosine Related Classifications
HY-W048303 Related Classifications
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